Q83JF9

PR
Gene name
infB
Protein name
Translation initiation factor IF-2
Names
Species
Shigella flexneri
KEGG Pathway
sfx:S3426
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

116-316 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q83JF9

Entry ID Method Resolution Chain Position Source
AF-Q83JF9-F1 Predicted AlphaFoldDB

No variants for Q83JF9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q83JF9

No associated diseases with Q83JF9

7 regional properties for Q83JF9

Type Name Position InterPro Accession
domain Translational (tr)-type GTP-binding domain 381 - 550 IPR000795
domain Small GTP-binding protein domain 385 - 540 IPR005225
domain Translation initiation factor IF-2, N-terminal 1 - 52 IPR006847-1
domain Translation initiation factor IF-2, N-terminal 306 - 356 IPR006847-2
domain Initiation factor 2 associated domain, bacterial 56 - 94 IPR013575
domain Translation initiation factor IF- 2, domain 3 657 - 771 IPR023115
domain Translation initiation factor IF-2, domain II 557 - 650 IPR044145

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
GTP binding Binding to GTP, guanosine triphosphate.
GTPase activity Catalysis of the reaction: GTP + H2O = GDP + H+ + phosphate.
translation initiation factor activity Functions in the initiation of ribosome-mediated translation of mRNA into a polypeptide.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MTDVTIKTLA AERQTSVERL VQQFADAGIR KSADDSVSAQ EKQTLIDHLN QKNSGPDKLT
70 80 90 100 110 120
LQRKTRSTLN IPGTGGKSKS VQIEVRKKRT FVKRDPQEAE RLAAEEQARR EAEESAKREA
130 140 150 160 170 180
QQKAEREAAE QAKREAAEQA KREAAEKDKV SNQQDDMTKN AQAEKARREQ EAAELKRKAE
190 200 210 220 230 240
EEARRKLEEE ARRVAEEARR MAEENKWTDN AEPTEDSSDY HVTTSQHARQ AEDESDREVE
250 260 270 280 290 300
GGRGRGRNAK AARPKKGNKH AESKADREEA RAAVRGGKGG KRKGSSLQQG FQKPAQAVNR
310 320 330 340 350 360
DVVIGETITV GELANKMAVK GSQVIKAMMK LGAMATINQV IDQETAQLVA EEMGHKVILR
370 380 390 400 410 420
RENELEEAVM SDRDTGAAAE PRAPVVTIMG HVDHGKTSLL DYIRSTKVAS GEAGGITQHI
430 440 450 460 470 480
GAYHVETENG MITFLDTPGH AAFTSMRARG AQATDIVVLV VAADDGVMPQ TIEAIQHAKA
490 500 510 520 530 540
AQVPVVVAVN KIDKPEADPD RVKNELSQYG ILPEEWGGES QFVHVSAKAG TGIDELLDAI
550 560 570 580 590 600
LLQAEVLELK AVRKGMASGA VIESFLDKGR GPVATVLVRE GTLHKGDIVL CGFEYGRVRA
610 620 630 640 650 660
MRNELGQEVL EAGPSIPVEI LGLSGVPAAG DEVTVVRDEK KAREVALYRQ GKFREVKLAR
670 680 690 700 710 720
QQKSKLENMF ANMTEGEVHE VNIVLKADVQ GSVEAISDSL LKLSTDEVKV KIIGSGVGGI
730 740 750 760 770 780
TETDATLAAA SNAILVGFNV RADASARKVI EAESLDLRYY SVIYNLIDEV KAAMSGMLSP
790 800 810 820 830 840
ELKQQIIGLA EVRDVFKSPK FGAIAGCMVT EGVVKRHNPI RVLRDNVVIY EGELESLRRF
850 860 870 880
KDDVNEVRNG MECGIGVKNY NDVRTGDVIE VFEIIEIQRT IA