Q83944

PR
Gene name
ORF2a
Protein name
RNA-directed RNA polymerase 2a
Names
protein 2a
Species
Olive latent virus 2 (isolate Italy) (OLV-2)
KEGG Pathway
vg:991142
EC number
2.7.7.48: Nucleotidyltransferases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

226-342 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q83944

Entry ID Method Resolution Chain Position Source

No variants for Q83944

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q83944

No associated diseases with Q83944

2 regional properties for Q83944

Type Name Position InterPro Accession
domain RNA-dependent RNA polymerase, alsuviricetes 311 - 732 IPR001788
domain RNA-directed RNA polymerase, catalytic domain 505 - 619 IPR007094

Functions

Description
EC Number 2.7.7.48 Nucleotidyltransferases
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

3 GO annotations of molecular function

Name Definition
nucleotide binding Binding to a nucleotide, any compound consisting of a nucleoside that is esterified with (ortho)phosphate or an oligophosphate at any hydroxyl group on the ribose or deoxyribose.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA-directed 5'-3' RNA polymerase activity Catalysis of the reaction: nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1); uses an RNA template, i.e. the catalysis of RNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.

2 GO annotations of biological process

Name Definition
DNA-templated transcription The synthesis of an RNA transcript from a DNA template.
viral RNA genome replication The replication of a viral RNA genome.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAGVLYDEEY VPQEPDYLYC PYEWEGEDPT QCDANVPSVS YLVEAVKKSF TEGNHDMLIS
70 80 90 100 110 120
CESYHAECCE GPLMNKGLTL STYFMSYPGI SLPAFGGGVI HVTSARVCMQ AFYAVTPGRC
130 140 150 160 170 180
SCSCGTQFIY RAKGGTGLTF DATNTISSAF KFEDGKVKWL TEDLGLALLA GCFLKYVPIP
190 200 210 220 230 240
HEIEIKIERK VEPVSALDFW EPEGLISDVH FVHPQERALA PEPPMDVEMV RLVRTELFEH
250 260 270 280 290 300
FNPTLLLNAR SDFSGEKLKE VELPRAQSEP LVPRVCLPRG DDALIDQFFI DKAPEHFNRE
310 320 330 340 350 360
PATDQWQVES DDFTVDFPTQ VRLRERDEDW FRRKPDFAVS SIRTGLEMPR IATKKEMLMA
370 380 390 400 410 420
FSKRNVGAPQ MVEVPQEIHV KRLADRFFRT FLKEGGWDKG DGHYWDDFFH RKGRKVFSLE
430 440 450 460 470 480
NCYDDPLSSY LVMLKSAGKF SLDLNFPVRS VPQTITYHEK WVTEVFSPMF LQVMARFFSR
490 500 510 520 530 540
LQDWVVVPAG PMADFSRVWP SFEGKCLTEI DLSKFDKSQG KLLHDVQREI FLRLGFPPIW
550 560 570 580 590 600
CDWWFKFHES SYLNDKNLGI AFSVDYQRRT GNTATYFGNT LVTMIMMAEV YELDSLPFCG
610 620 630 640 650 660
LFSGDDNLIV TDRPLEGRVS LFPNMFNMEA KVMRPGQNYM CSKYLCTVDG RVTPVPDPFK
670 680 690 700 710 720
LLKKAGASCP LEHLDDFYES FLDYTKYLVR DEVRTLIPRL MAHRYQVSMD EAGVALDQIM
730 740 750 760 770 780
SWRKSKTQFF KHFQYRKPIK DSLEAVKSDF LSAFGKVDDR IRVWRGRRTN HKKEVDALKV
PLVSFRE