Q83943

PR
Gene name
ORF1a
Protein name
Replication protein 1a
Names
Species
Olive latent virus 2 (isolate Italy) (OLV-2)
KEGG Pathway
vg:991141
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

104-175 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q83943

Entry ID Method Resolution Chain Position Source

No variants for Q83943

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q83943

No associated diseases with Q83943

2 regional properties for Q83943

Type Name Position InterPro Accession
domain Alphavirus-like methyltransferase (MT) domain 48 - 339 IPR002588
domain (+) RNA virus helicase core domain 599 - 908 IPR027351

Functions

Description
EC Number
Subcellular Localization
  • Host endoplasmic reticulum membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
host cell endoplasmic reticulum membrane The lipid bilayer surrounding the host cell endoplasmic reticulum.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

5 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
helicase activity Catalysis of the reaction: ATP + H2O = ADP + phosphate, to drive the unwinding of a DNA or RNA helix.
hydrolase activity Catalysis of the hydrolysis of various bonds, e.g. C-O, C-N, C-C, phosphoric anhydride bonds, etc.
mRNA methyltransferase activity Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a nucleoside residue in an mRNA molecule.
RNA binding Binding to an RNA molecule or a portion thereof.

1 GO annotations of biological process

Name Definition
RNA processing Any process involved in the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDSAALEKMT GAKFPAVQGV IEEFSRDRVQ NVLGDMRSRQ VIKYAVGLSE ASVQELRFNW
70 80 90 100 110 120
PCFTWEEESV PLPPHPFAAY SRRAFTRWAI AQCGPVPIKD FGGNWFLHWQ WQTGVHSCCP
130 140 150 160 170 180
LLNPRDGAHQ TRRELNMESY LRTHGPKYDK FNELSRPDLC HHRAEDCSVR AKAALSVDSA
190 200 210 220 230 240
YDMGLKNTCK AMHRAGIELL HGNILFDPDM LIEAKMEGFV AGMNYHWKKT RRSTGLMSSF
250 260 270 280 290 300
LEMGSSLFGV SNSSKEGEGH HDLKIKMGSS STHMVPADWE ISYHFRDDCV LGYTHNLADV
310 320 330 340 350 360
LSIATGSYVK VGNTFYELER TGLKSGMLMY TITACKGLYD RASARSTPLS AKASTVIING
370 380 390 400 410 420
MSYQVGEKLD PISFPYLAAS FYMQAQKAVF EVQQVVDLHT PNRNLWSWFK KKFELKAHAF
430 440 450 460 470 480
LFALGLRDSH DEWLLDQIEF ELNETVCTLP GEFLEPVSEV ERLDAALEDW RRDRERLNGK
490 500 510 520 530 540
SVENLKTLTV LVELAKKLGI SAYEVLNSHQ NESERPKDQW HVEAALFEAV ELERAHWKML
550 560 570 580 590 600
TAEAQAMSLQ DPLSREAKSK GWSYESSDSL PCAYAYVFSE GRFVKPADLK KKTRVLVSPS
610 620 630 640 650 660
MQIMNQIRMA ESLEKAIAMN VKSCKKTWID GVAGCGKTYE IVHTADIFKK DDLILTANKK
670 680 690 700 710 720
SQEDIFSQLK PGTDCAKRIR TVDSYLLKPD VQAKRLFIDE AGLVHPGKLL AAMRFAECDD
730 740 750 760 770 780
CLLFGDSEQI PFVNIVESLQ PAKFLKLEVD AREVRETTYR CPADVTATLA TLYKKKKIVT
790 800 810 820 830 840
KSKVLKSVTS KSLASASAVS GLDPHSWHLT MYQADKAELV RVARTNQMDD VWIKEHIKTV
850 860 870 880 890 900
HEAQGISVPH VKLYRFKTFD QPLFDAAHAE AYRLVAISRH TQSFTYIGVN QHLCKADRML
KFVICQIP