Q834A7

PR
Gene name
secA
Protein name
Protein translocase subunit SecA
Names
Species
Enterococcus faecalis (strain ATCC 700802 / V583)
KEGG Pathway
efa:EF1763
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

535-614 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q834A7

Entry ID Method Resolution Chain Position Source
AF-Q834A7-F1 Predicted AlphaFoldDB

No variants for Q834A7

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q834A7

No associated diseases with Q834A7

9 regional properties for Q834A7

Type Name Position InterPro Accession
domain Helicase, C-terminal 414 - 569 IPR001650
conserved_site SEC-C motif 825 - 843 IPR004027
domain SecA DEAD-like, N-terminal 5 - 382 IPR011115
domain SecA Wing/Scaffold 570 - 778 IPR011116
domain SecA, preprotein cross-linking domain 226 - 338 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 87 - 225 IPR014001
domain SecA motor DEAD 1 - 570 IPR014018
conserved_site SecA conserved site 480 - 495 IPR020937
domain SecA, C-terminal helicase domain 400 - 540 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
metal ion binding Binding to a metal ion.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MANFLKKMIE NDKKELRRLE KIADKIDAHA SAMEQLSDEQ LREKTDEFKA RYQKGETLDE
70 80 90 100 110 120
LLPEAFAVVR EAAKRVLGLF PYRVQLMGGI VLHDGNIPEM RTGEGKTLTA TMPVYLNALS
130 140 150 160 170 180
GEGVHVVTVN EYLATRDSNE MGELYNFLGL SVGLNINSKS SDEKREAYNC DITYSTNNEL
190 200 210 220 230 240
GFDYLRDNMV VYRSQMVQRP LNYAIVDEVD SILIDEARTP LIISGQAEKS TALYTRADNF
250 260 270 280 290 300
VKRLKEDEDY KIDIQSKTIG LTEAGIEKAE QTFGLDNLYD IENTALTHHL DQALRANYIM
310 320 330 340 350 360
LLDIDYVVQD NKVLIVDQFT GRIMDGRRYS DGLHQAIEAK EGVEIEDETK TMATITFQNY
370 380 390 400 410 420
FRMYKKLAGM TGTAKTEEEE FREIYNIQVI QIPTNRPIIR DDRPDLLYPT LESKFNAVVE
430 440 450 460 470 480
DIKERYHKGQ PVLVGTVAVE TSELLSDKLN AAKIPHEVLN AKNHFKEAEI IMNAGQKGAV
490 500 510 520 530 540
TIATNMAGRG TDIKLGLGVL ELGGLAVIGT ERHESRRIDN QLRGRAGRQG DPGVSQFYLS
550 560 570 580 590 600
LEDDLMKRFG SERIKTFLER MNVQEEDAVI QSKMFTRQVE SAQKRVEGNN YDTRKNVLQY
610 620 630 640 650 660
DDVMREQREV IYAQRQEVIM EENDLSDVLM GMVKRTIGRV VDSHTQLEKE EWNLDGIVDF
670 680 690 700 710 720
AASTLVHEDT ISKKDLENKS AEEIKDYLVA RAQEVFEEKS QQLNGQEQLL EFEKVVILRV
730 740 750 760 770 780
VDTKWTDHID AMDQLRQSVG LRAYGQNNPL VEYQTEGYSM YNNMVGSIEY EVTRLFMKSE
790 800 810 820 830 840
IRQNVQREQV AQGQAEHPET EQDAAAQSNT SAKRQPVRVD KKVGRNDLCP CGSGKKFKNC
HGRNA