Q82U08

PR
Gene name
mutS
Protein name
DNA mismatch repair protein MutS
Names
Species
Nitrosomonas europaea (strain ATCC 19718 / CIP 103999 / KCTC 2705 / NBRC 14298)
KEGG Pathway
neu:NE1705
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

780-864 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q82U08

Entry ID Method Resolution Chain Position Source
AF-Q82U08-F1 Predicted AlphaFoldDB

No variants for Q82U08

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q82U08

No associated diseases with Q82U08

5 regional properties for Q82U08

Type Name Position InterPro Accession
domain DNA mismatch repair protein MutS, C-terminal 621 - 811 IPR000432
domain DNA mismatch repair protein MutS-like, N-terminal 10 - 120 IPR007695
domain DNA mismatch repair protein MutS, core 278 - 602 IPR007696
domain DNA mismatch repair protein MutS, connector domain 139 - 248 IPR007860
domain DNA mismatch repair protein MutS, clamp 439 - 529 IPR007861

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP-dependent DNA damage sensor activity A molecule that recognises toxic DNA structures, and initiates a signalling response, driven by ATP hydrolysis.
damaged DNA binding Binding to damaged DNA.
mismatched DNA binding Binding to a double-stranded DNA region containing one or more mismatches.

1 GO annotations of biological process

Name Definition
mismatch repair A system for the correction of errors in which an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. The mismatch repair system promotes genomic fidelity by repairing base-base mismatches, insertion-deletion loops and heterologies generated during DNA replication and recombination.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNKAEQSSHT PMMQQYLRIK AQHTDKLLFY RMGDFYELFY EDAEKAAKLL DITLTQRGSS
70 80 90 100 110 120
AGEPIKMAGV PFHAADQYLA RLVRLGESIA ICEQTGDPAT SKGPVERQVI RILTPGTLTD
130 140 150 160 170 180
AGLLEERSNS IVLALALHRG SIGLAWLNLA AGDMRVLETS SDNLTSELER LHPAEILLPE
190 200 210 220 230 240
SLDLPATLNN FAGPKRLPDW QFDYEHAMQQ LTRQFGTRDL NAFGCEDLHA AIMAAGALFE
250 260 270 280 290 300
YVRLTQQTAT DGSSGQLPGH LHTLQVERQD AYLRMDAATR RNLEITLTLR GEDAPTLSSL
310 320 330 340 350 360
LDTCSTGMGS RLLRHWLHHP LRNRITLQQR LDTVSDLIGA QPETLYAGIR QQFKHIADIE
370 380 390 400 410 420
RITSRIALRT ARPRDLSGLR DSLMRLPGII ELIATSAAAA VHRFIPPMQP DPLLTQLLVR
430 440 450 460 470 480
ALQPVPGAVI REGGVIADGF DAELDELRGL QGNCDEFLLQ LEARERERTG IPNLKVEYNR
490 500 510 520 530 540
VHGFYIEVTR AQGEKIPPDY RRRQTLKNAE RYIIPELQAF EHKTLSAREQ ALAREKMLYE
550 560 570 580 590 600
RLLEQLADFI IPLQEIARSV AELDVLCAFA ERAALSGYTK PVFTDDPVLI IEAGRHPVVE
610 620 630 640 650 660
NQVEHYIAND VQLGAITREN RQMLVITGPN MGGKSTYMRQ TALTVLLAHC GSFVPAQIAR
670 680 690 700 710 720
IGPIDQIFTR IGAADDLAGG RSTFMVEMTE AAGILRNATA QSLVLVDEIG RGTSTFDGLA
730 740 750 760 770 780
LAFAIARHLL TQNQSYTLFA THYFELTRLA EEFPQAVNIH VTAVEHKRRI VFLHRIEEGP
790 800 810 820 830 840
ASRSYGLHVA ALAGVPDRVI RNAAKILARL EQETLSRSPQ QTLFETVEEN AKAVPASVHP
850 860 870
VLDYLERIHP DELTPRGALE QLYLIKSMLN QTD