Q82KI9
Gene name |
tdk |
Protein name |
Thymidine kinase |
Names |
|
Species |
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) |
KEGG Pathway |
sma:SAVERM_2414 |
EC number |
2.7.1.21: Phosphotransferases with an alcohol group as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q82KI9
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q82KI9-F1 | Predicted | AlphaFoldDB |
No variants for Q82KI9
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q82KI9 | |||||
No associated diseases with Q82KI9
No regional properties for Q82KI9
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| No domain, repeats, and functional sites for Q82KI9 | |||
Functions
| Description | ||
|---|---|---|
| EC Number | 2.7.1.21 | Phosphotransferases with an alcohol group as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| thymidine kinase activity | Catalysis of the reaction: ATP + thymidine = ADP + thymidine 5'-phosphate. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| DNA biosynthetic process | The biosynthetic process resulting in the formation of DNA. |
| phosphorylation | The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPELVFFSGT | MDCGKSTLAL | QIGHNRSARG | LQGVIFTRDD | RAGEGKLSSR | LGLVTEAVEA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| APGMDLHAYL | VDQMSKGGKV | DYLIVDEAQF | LAPEQIDQLA | RVVDDLDLDV | FAFGITTDFR |
| 130 | 140 | 150 | 160 | 170 | 180 |
| TKLFPGSQRL | IELADRIETL | QVEAMCWCGA | RATHNARTVG | GEMVVEGEQV | VVGDVNRPAA |
| 190 | 200 | 210 | |||
| EVGYEVLCRR | HHRRRMTSAS | AYAAAISPDV | LPVTSA |