Q82K39

PR
Gene name
secA2
Protein name
Protein translocase subunit SecA 2
Names
Species
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
KEGG Pathway
sma:SAVERM_2565
EC number
7.4.2.8: Linked to the hydrolysis of a nucleoside triphosphate
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

834-920 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q82K39

Entry ID Method Resolution Chain Position Source
AF-Q82K39-F1 Predicted AlphaFoldDB

No variants for Q82K39

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q82K39

No associated diseases with Q82K39

8 regional properties for Q82K39

Type Name Position InterPro Accession
domain Helicase, C-terminal 438 - 645 IPR001650
domain SecA DEAD-like, N-terminal 10 - 417 IPR011115
domain SecA Wing/Scaffold 638 - 852 IPR011116
domain SecA, preprotein cross-linking domain 232 - 366 IPR011130
domain Helicase superfamily 1/2, ATP-binding domain 93 - 238 IPR014001
domain SecA motor DEAD 7 - 640 IPR014018
conserved_site SecA conserved site 515 - 530 IPR020937
domain SecA, C-terminal helicase domain 435 - 610 IPR044722

Functions

Description
EC Number 7.4.2.8 Linked to the hydrolysis of a nucleoside triphosphate
Subcellular Localization
  • Cell membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Cytoplasm
  • Distribution is 50-50
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
protein-exporting ATPase activity Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + protein+(in) -> ADP + phosphate + protein+(out); drives the concomitant secretion of proteins.

3 GO annotations of biological process

Name Definition
intracellular protein transmembrane transport The directed movement of proteins in a cell, from one side of a membrane to another by means of some agent such as a transporter or pore.
protein import The targeting and directed movement of proteins into a cell or organelle. Not all import involves an initial targeting event.
protein targeting The process of targeting specific proteins to particular regions of the cell, typically membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPVLGLDNIT GRIMRAGEGR ILRRLQRIAA QVNSLEEEFK ALTDEELQAL TPEFTRRHAD
70 80 90 100 110 120
GESLDDLLPE AFATMREAAR RTLGMRHFDV QLMGGAALHF GNIAEMQTGE GKTLVGTLPV
130 140 150 160 170 180
YLNALTGKGV HLVTVNDYLA ERDAEWMGRA YRFLGLTVGV IKSQSTPAER RAQYACDITY
190 200 210 220 230 240
GTNTEFGFDY LRDNMAWSQD ELVQRGHHFA IVDEADSILI DEARTPLIIS GPADQPTQWY
250 260 270 280 290 300
GAFAKLVTRM RGVRVQEEQF VTPADKDRLA HLRTTHDYEY DPKKRTVAIL DRGVEYLQDQ
310 320 330 340 350 360
LGIESLYESE HTSLIGHLNN ALKAKEHFRK DKDYVVVDGE VLIVDEHTGR ILAGRRYNEG
370 380 390 400 410 420
LHQAIEAKEA EEGTEAGVTV RNENQTLATI TLQNFFRLYE KLAGMTGTAM TEAAEFHQIY
430 440 450 460 470 480
QLNVVPIPSN RPMIRRDDPD QIYRTEEAKY AAILADIAER HETGQPILVG TTSVEKSELL
490 500 510 520 530 540
SGLLRKQGIR HEVLNAKNHQ REAQIVAQAG RRGAVTVATN MAGRGTDIML GGNPEAMALA
550 560 570 580 590 600
ALPEDATPED REAVLDRVGR AAAAEHEEVK ELGGLYVLGT ERHESRRIDN QLRGRSGRQG
610 620 630 640 650 660
DPGASRFYLS LGDDLMRLFR AQVVERVMSM ANVPDDVPIE NKMVTRAIAS AQSQLEQQHF
670 680 690 700 710 720
ESRKDVLKFD EVLNRQRTLI YAERRRVLAG EDLREQVRHF MDDTIEAYIR QETGEGFPEE
730 740 750 760 770 780
WDLERLWGAF RQLYPVGITI EDLEDSVGGR PDLTVDDLVA AVTEDVHDRY ARREAELGAD
790 800 810 820 830 840
ALRDLERLVV LSVLDRKWRE HLYEMDYLRD GIGLRWTLGR EPIVEYEREG FDMFGAMTEA
850 860 870 880 890 900
IKEESVGYVF NLDATGREGE GSALDRRPTD GLHFSAPTLD TAEGVVEGRF TTAPAGEPAE
910
HDKAPPHRPG KSRNRRRRKR