Q828Y9

PR
Gene name
cmk
Protein name
Cytidylate kinase
Names
CK, Cytidine monophosphate kinase, CMP kinase
Species
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680)
KEGG Pathway
sma:SAVERM_6522
EC number
2.7.4.25: Phosphotransferases with a phosphate group as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

134-225 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q828Y9

Entry ID Method Resolution Chain Position Source
AF-Q828Y9-F1 Predicted AlphaFoldDB

No variants for Q828Y9

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q828Y9

No associated diseases with Q828Y9

1 regional properties for Q828Y9

Type Name Position InterPro Accession
domain Cytidylate kinase domain 13 - 225 IPR011994

Functions

Description
EC Number 2.7.4.25 Phosphotransferases with a phosphate group as acceptor
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
CMP kinase activity Catalysis of the reaction: ATP + CMP = ADP + CDP.
dCMP kinase activity Catalysis of the reaction: ATP + dCMP = ADP + dCDP.

2 GO annotations of biological process

Name Definition
phosphorylation The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
pyrimidine nucleotide metabolic process The chemical reactions and pathways involving a pyrimidine nucleotide, a compound consisting of nucleoside (a pyrimidine base linked to a deoxyribose or ribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MENGAARTVP AVIVAIDGPS GTGKSSTSKA VAAKLGLSYL DTGAQYRAIT WWMVSNGIDI
70 80 90 100 110 120
TDPTAIAAVA GKPEIISGTD PSAPTITVDG TDVAAPIRTQ EVTSKVSAVS AVPEVRTRIT
130 140 150 160 170 180
ELQRSLATSA ENGIVVEGRD IGTTVLPDAD LKIFLTASPE ARAARRSGEL KGADVNSTRE
190 200 210 220 230
ALLKRDAADS SRKTSPLAKA DDAVEVDTSD LTLQQVIECV VTLVEEKRAA K