Q826F6
Gene name |
dnaK2 (SAV_7237) |
Protein name |
Chaperone protein dnaK2 |
Names |
HSP70-2, Heat shock 70 kDa protein 2, Heat shock protein 70-2 |
Species |
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) |
KEGG Pathway |
sma:SAVERM_7237 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q826F6
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q826F6-F1 | Predicted | AlphaFoldDB |
No variants for Q826F6
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q826F6 | |||||
No associated diseases with Q826F6
3 regional properties for Q826F6
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Heat shock protein 70, conserved site | 7 - 14 | IPR018181-1 |
| conserved_site | Heat shock protein 70, conserved site | 189 - 202 | IPR018181-2 |
| conserved_site | Heat shock protein 70, conserved site | 330 - 344 | IPR018181-3 |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP-dependent protein folding chaperone | Binding to a protein or a protein-containing complex to assist the protein folding process, driven by ATP hydrolysis. |
| unfolded protein binding | Binding to an unfolded protein. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAKAVGIDLG | TTNSVIAVWE | GGEPSVVPNS | EGNRTTPSVV | AFTDTGERLV | GQLARRQAIL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NPKGTIYSAK | RFIGRHFDEI | SDEARAVTYD | VVEGDGGAAR | FKVRDKLYAP | EEISAQVLRK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LADDASKQLG | ERVTEAVITV | PAYFNDAQRT | ATKDAGRIAG | LEVLRIINEP | TAAALAYGMD |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KKEHETVLVF | DLGGGTFDVS | ILDVGDGVVE | VRSTAGDSHL | GGDDFDRRLV | DYLADDFQQE |
| 250 | 260 | 270 | 280 | 290 | 300 |
| NGIDLRKDPQ | ALQRLFEAAE | KAKTELSSVT | QTQVSLPFIT | ADASGPKHLT | DTVMRSTFEQ |
| 310 | 320 | 330 | 340 | 350 | 360 |
| ITSDLVERCL | GPVQQAMADA | KVGESDIDEV | ILVGGSTRIP | AVQALVRRLT | GGKDPNMSVN |
| 370 | 380 | 390 | 400 | 410 | 420 |
| PDEVVALGAA | IQAGVLKGEV | KDVLLLDVTP | LSLGVETRGG | VMTKIIERNT | TIPVRRSETF |
| 430 | 440 | 450 | 460 | 470 | 480 |
| STAEDNQPAV | DVVVLQGERE | RAADNRVLGR | FQLTDIRPAP | RGEPQVEVTF | DIDANGILNV |
| 490 | 500 | 510 | 520 | 530 | 540 |
| TARDKDTGKE | QGITISESSN | LDRSEVERMV | QEAERNQGQD | QALREAVDAR | NELDAVAYQV |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EKRLAELGDA | APAHEKARAE | MLVSDARAAV | KEEAGVERVR | PLTSELQQVL | AGLAAHQGAA |
| 610 | 620 | 630 | |||
| TADGGPAQHA | ATGGPTSGGG | GGDDVIDAEF | DKG |