Q826F2
Gene name |
clpB2 (SAV_7241) |
Protein name |
Chaperone protein ClpB 2 |
Names |
|
Species |
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NBRC 14893 / NCIMB 12804 / NRRL 8165 / MA-4680) |
KEGG Pathway |
sma:SAVERM_7241 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q826F2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q826F2-F1 | Predicted | AlphaFoldDB |
No variants for Q826F2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q826F2 | |||||
No associated diseases with Q826F2
9 regional properties for Q826F2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | AAA+ ATPase domain | 203 - 348 | IPR003593-1 |
| domain | AAA+ ATPase domain | 605 - 758 | IPR003593-2 |
| domain | ATPase, AAA-type, core | 208 - 340 | IPR003959-1 |
| domain | ATPase, AAA-type, core | 604 - 770 | IPR003959-2 |
| domain | Clp, repeat (R) domain | 3 - 151 | IPR004176 |
| conserved_site | ClpA/B, conserved site 1 | 299 - 311 | IPR018368 |
| domain | Clp ATPase, C-terminal | 776 - 865 | IPR019489 |
| conserved_site | ClpA/B, conserved site 2 | 639 - 657 | IPR028299 |
| domain | ClpA/ClpB, AAA lid domain | 347 - 449 | IPR041546 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| ATP binding | Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
| ATP hydrolysis activity | Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| protein refolding | The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones. |
| response to heat | Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDMNRLTQKS | QEALQEAQTA | AGRMGHTEVD | GEHLLLALLD | QEDGLIPRLL | QQAGTEPKEL |
| 70 | 80 | 90 | 100 | 110 | 120 |
| RAAVREELSH | RPKATGPGAA | PGQVFVTQRL | ARLLDAAERE | AKRLKDEYVS | VEHLLLALAE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ESSSTAAGLL | LKQAGITRDS | FLSALTQVRG | NQRVTSANPE | VAYEALEKYG | RDLVLEARSG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| RLDPVIGRDA | EIRRVTQILS | RKTKNNPVLI | GDPGVGKTAI | VEGLAQRIVR | GDVPEGLRDK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TVFALDMGSL | VAGAKYRGEF | EERLKAVLSE | VKAAEGRILL | FVDELHTVVG | AGAAEGAMDA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GNMLKPMLAR | GELHMIGATT | LDEYRKHIEK | DAALERRFQQ | VLVDEPSVED | TISILRGLRE |
| 370 | 380 | 390 | 400 | 410 | 420 |
| RLEVFHGVKI | QDTALVSAAT | LSHRYITDRF | LPDKAIDLVD | EACARLRTEI | DSMPAELDEI |
| 430 | 440 | 450 | 460 | 470 | 480 |
| TRRVTRLEIE | EAALSKESDP | ASKTRLEELR | RELADLRGEA | DAKHAQWEAE | RQAIRRVQEL |
| 490 | 500 | 510 | 520 | 530 | 540 |
| RQELEQVRHE | AEEAERAYDL | NRAAELRYGR | LQDLERRLAA | EEEQLAAKQG | ENRLLREVVT |
| 550 | 560 | 570 | 580 | 590 | 600 |
| EEEIAEIVAA | WTGIPVARLQ | EGEREKLLRL | DEILRERVIG | QDEAVKLVTD | AIIRARSGIR |
| 610 | 620 | 630 | 640 | 650 | 660 |
| DPRRPIGSFI | FLGPTGVGKT | ELAKTLARTL | FDSEENMVRL | DMSEYQERHT | VSRLMGAPPG |
| 670 | 680 | 690 | 700 | 710 | 720 |
| YVGYEEGGQL | TEAVRRKPYS | VVLFDEIEKA | HTDVFNTLLQ | ILDDGRITDA | QGRTVDFRNT |
| 730 | 740 | 750 | 760 | 770 | 780 |
| VIIMTSNIGS | EHLLDGATAE | GEIKPDARAL | VMGELRGHFR | PEFLNRVDDI | VLFKPLGERQ |
| 790 | 800 | 810 | 820 | 830 | 840 |
| IERIVELQFD | ELRQRLAERR | ITVELTDAGR | EVIAHQGYDP | VYGARPLRRY | ISHEVETLVG |
| 850 | 860 | 870 | |||
| RALLRGDVQD | GATVRVDAEH | GELVVTYDQP | EDVKGAWAA |