Q82446

PR
Gene name
ORF2
Protein name
Capsid polyprotein VP90
Names
Species
Human astrovirus-2 (HAstV-2)
KEGG Pathway
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-118 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

2 structures for Q82446

Entry ID Method Resolution Chain Position Source
5KOU X-ray 187 A A/B/C/D 429-644 PDB
5KOV X-ray 325 A A/B/G/H/M/N/S/T 429-644 PDB

No variants for Q82446

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q82446

No associated diseases with Q82446

No regional properties for Q82446

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q82446

Functions

Description
EC Number
Subcellular Localization
  • Virion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
T=3 icosahedral viral capsid The protein coat that surrounds the infective nucleic acid in some virus particles where the subunits (capsomeres) are arranged to form an icosahedron with T=3 symmetry. The T=3 capsid is composed of 12 pentameric and 20 hexameric capsomeres.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
clathrin-dependent endocytosis of virus by host cell Any clathrin-mediated endocytosis that is involved in the uptake of a virus into a host cell. Begins by invagination of a specific region of the host cell plasma membrane around the bound virus to form a clathrin-coated pit, which then pinches off to form a clathrin-coated endocytic vesicle containing the virus.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASKSDKQVT VEVNNNGRNR SKSRARSQSR GRGRSVKITV NSHNKGRRQN GRNKYQSNQR
70 80 90 100 110 120
VRKIVNKQLR KQGVTGPKPA ICQRATATLG TIGTNTTGAT EIEACILLNP VLVKDATGST
130 140 150 160 170 180
QFGPVQALGA QYSMWKLKYL NVKLTSMVGA SAVNGTVLRI SLNPTSTPSS TSWSGLGARK
190 200 210 220 230 240
HMDVTVGRNA VFKLRPSDLG GPRDGWWLTN TNDNASDTLG PSIEIHTLGK TMSSYKNEQF
250 260 270 280 290 300
TGGLFLVELA SEWCFTGYAA NPNLVNLVKS TDHEVNVTFE GSKGTPLIMN VAEHSHFARM
310 320 330 340 350 360
AEQHSSISTT FSRAGGDATS DTVWQVLNTA VSAAELVAPP PFNWLIKGGW WFVKLIAGRT
370 380 390 400 410 420
RTGTKQFYVY PSYQDALSNK PALCTGGVTG GVLRTTPVTT LQFTQMNQPS LGHGEHTATI
430 440 450 460 470 480
GSIVQDPSGE LRVLLTVGSI MSPNSADRQV WLNKTLTAPG TNSNDNLVKI AHDLGHYLIM
490 500 510 520 530 540
QGFMHIKTVE WYTPDFQPSR DPTPIAGMSV MVNITKKADV YFMKQFKNSY TNNRHQITSI
550 560 570 580 590 600
FLIKPLADFK VQCYMSYFKR ESHDNDGVAN LTVRSMTSPE TIRFQVGEWY LLTSTTLKEN
610 620 630 640 650 660
NLPEGWVWDR VELKSDTPYY ADQALTYFIT PPPVDSQILF EGNTTLPRIS SPPDNPSGRY
670 680 690 700 710 720
MESHQQDCDS SDDEDDCENV SEETETEDEE DEDEDDEADR FDLHSPYSSE PEDSDENNRV
730 740 750 760 770 780
TLLSTLINQG MTVERATRIT KRAFPTCAEK LKRSVYMDLL ASGASPSSAW SNACDEARNV
790
GSNQLAKLSG DRGHAE