Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q81WP2

Entry ID Method Resolution Chain Position Source
AF-Q81WP2-F1 Predicted AlphaFoldDB

No variants for Q81WP2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q81WP2

No associated diseases with Q81WP2

6 regional properties for Q81WP2

Type Name Position InterPro Accession
domain Peptidase M41 437 - 624 IPR000642
domain AAA+ ATPase domain 220 - 359 IPR003593
domain ATPase, AAA-type, core 224 - 356 IPR003959
conserved_site ATPase, AAA-type, conserved site 327 - 345 IPR003960
domain Peptidase M41, FtsH extracellular 29 - 130 IPR011546
domain AAA ATPase, AAA+ lid domain 379 - 422 IPR041569

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Located at the septum
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

3 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAKQKQRGTK AKARRTIKPT LYYEIVGLTL FALSIITILQ LGVVGKSFVL FFRFFFGEWY
70 80 90 100 110 120
IIGVLGVIAL SVSFVIKRGW PNLLNKRLIG FYLIVLAILM FSHITLFNLL TKDGAVQNTS
130 140 150 160 170 180
VIVSTKDNFF LEMKKGPDSV HLGGGMFGAL MFATCYFLFD EVGAYIIGII LVILGILCIT
190 200 210 220 230 240
NKHIGEVLAP VGRILRSQFQ VMQGDYKDWR AKRTAEQTEK KKTTRSTRSK RATEQEEIIE
250 260 270 280 290 300
PMEEISIDPP IISNFTENYP VNEQEDKRIE VEQEELITSP FIEEAPPVEE PKKKRGEKIV
310 320 330 340 350 360
ESLEGETQAP PMQFSNVENK DYKLPALDIL KFPKNKQVTN ENAEIYENAR KLERTFQSFG
370 380 390 400 410 420
VKAKVTKVHR GPAVTKYEVY PDMGVKVSKI VGLSDDLALA LAAKDIRIEA PIPGKSAVGI
430 440 450 460 470 480
EVPNSEVSMV TLREVLDSKA NNHPEEKLLI GLGRDITGEA VLARLNKMPH LLVAGATGSG
490 500 510 520 530 540
KSVCINGIIV SILMRAKPHE VKLMMIDPKM VELNVYNGVP HLLTPVVTDP KKASQALKKV
550 560 570 580 590 600
VSEMERRYEL FAHSGTRNIE GYNDYIKEHN NQSEAKQPEL PYIVVIVDEL ADLMMVASSD
610 620 630 640 650 660
VEDAIMRLAQ MARAAGIHLI IATQRPSVDV ITGVIKANIP SRIAFAVSSQ TDSRTILDGG
670 680 690 700 710 720
GAEKLLGRGD MLFIPIGASK PVRVQGAFLS DDEVERVVEY VIGQQKAQYQ EDMIPQDVPD
730 740 750 760 770 780
TKQEVEDELY DEAVQLVVEM QTASVSMLQR RFRVGYTRAA RLIDAMEMNG VVGPYEGSKP
790
REVLINDVQE KSS