Q81C25

PR
Gene name
mqo
Protein name
Probable malate:quinone oxidoreductase
Names
MQO, Malate dehydrogenase [quinone]
Species
Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)
KEGG Pathway
bce:BC2959
EC number
1.1.5.4: With a quinone or similar compound as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

10-82 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q81C25

Entry ID Method Resolution Chain Position Source
AF-Q81C25-F1 Predicted AlphaFoldDB

No variants for Q81C25

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q81C25

No associated diseases with Q81C25

2 regional properties for Q81C25

Type Name Position InterPro Accession
conserved_site Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site 68 - 80 IPR018480-1
conserved_site Phospho-N-acetylmuramoyl-pentapeptide transferase, conserved site 189 - 200 IPR018480-2

Functions

Description
EC Number 1.1.5.4 With a quinone or similar compound as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

3 GO annotations of molecular function

Name Definition
malate dehydrogenase (menaquinone) activity Catalysis of the reaction: (S)-malate + a menaquinone = oxaloacetate + a menaquinol.
malate dehydrogenase (quinone) activity Catalysis of the reaction: (S)-malate + a quinone = oxaloacetate + a quinol.
oxidoreductase activity Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.

1 GO annotations of biological process

Name Definition
tricarboxylic acid cycle A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes successive transformations to isocitrate, 2-oxoglutarate, succinyl-CoA, succinate, fumarate, malate, and oxaloacetate again, thus completing the cycle. In eukaryotes the tricarboxylic acid is confined to the mitochondria. See also glyoxylate cycle.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MQQKTDVILI GAGIMSATLG SLLKELAPEW EIKVFEKLAS AGEESSNEWN NAGTGHSALC
70 80 90 100 110 120
ELNYTSEKAD GSIDISKAVK VNEQFQLSRQ FWAYLVKSKL IRNPQDFIMP LPHMSLVQGK
130 140 150 160 170 180
KNVEFLKNRF EALSKNPLFQ GMEFSDAPET LKKWLPLIME GRTSNEPMAA TKIDSGTDVN
190 200 210 220 230 240
FGALTRMLFD YLKTKNVELN YKHSVENIKR TKNGLWEVKV HDMNSGKIEH HTAKFVFIGG
250 260 270 280 290 300
GGGSLPLLQK TGIPESKHIG GFPVSGLFMV CKNQKVVEQH HAKVYGKAKV GAPPMSVPHL
310 320 330 340 350 360
DTRYIDNKKA LLFGPFAGFS PKFLKTGSNL DLIGSVKPNN VLTMLAAGVK EMGLTKYLIQ
370 380 390 400 410 420
QVMLSHEKRM LDFPAFIPNA KSEDWDIVVA GQRVQVIKDT DAGGKGTLQF GTEVVSAADG
430 440 450 460 470 480
SIAALLGASP GASTAVHVML EVLEKCFPSR MIEWEEKIKE MIPSYGISLT ENPRLFQDLH
490
TSTGRTLGLN EKETVHN