Q815E8

PR
Gene name
speE2
Protein name
Polyamine aminopropyltransferase 2
Names
Putrescine aminopropyltransferase, PAPT, Spermidine synthase, SPDS, SPDSY
Species
Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG 7414 / JCM 2152 / NBRC 15305 / NCIMB 9373 / NCTC 2599 / NRRL B-3711)
KEGG Pathway
bce:BC5213
EC number
2.5.1.16: Transferring alkyl or aryl groups, other than methyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-93 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q815E8

Entry ID Method Resolution Chain Position Source
AF-Q815E8-F1 Predicted AlphaFoldDB

No variants for Q815E8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q815E8

No associated diseases with Q815E8

2 regional properties for Q815E8

Type Name Position InterPro Accession
conserved_site Polyamine biosynthesis domain, conserved site 140 - 153 IPR030373
domain Polyamine biosynthesis domain 68 - 299 IPR030374

Functions

Description
EC Number 2.5.1.16 Transferring alkyl or aryl groups, other than methyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
spermidine synthase activity Catalysis of the reaction: S-adenosylmethioninamine + putrescine = 5'-methylthioadenosine + spermidine.

2 GO annotations of biological process

Name Definition
polyamine biosynthetic process The chemical reactions and pathways resulting in the formation of polyamines, any organic compound containing two or more amino groups.
spermidine biosynthetic process The chemical reactions and pathways resulting in the formation of spermidine, N-(3-aminopropyl)-1,4-diaminobutane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MPKHRKQSKI KIYRITSYKK DKRSELDSDK FELEQQDKHD IQDKQDKQDE QNKQDKQVQS
70 80 90 100 110 120
ENVTIVPTDS HSLDVWDEIS LKEIQAGEHT SLFEEKSNYQ NINLVQVNDV RLYLDKQLQF
130 140 150 160 170 180
SSVDEQIYHE ALVHPIMAKV IDPKRVLILG GGDGLALREV LKYETVLHVD LVDLDEAMIN
190 200 210 220 230 240
MARNVPEIVS LNKNAFFDNR VNVHVCDAKE FLNSPSSLYD VIIIDFPDPA TELLSTLYTS
250 260 270 280 290 300
ELFARIATFL TEDGAFVCQS NSPADAPLVY WSIGNTIEHA GLTVKSYHTI VPSFGTDWGF
310 320 330 340 350 360
HLATNSAHVL DQIEQLYVVP TPRTLPALLF PLFQFKEEHL EQRNLALLNS ESNLILHQCY
KQEMKF