Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q814I2

Entry ID Method Resolution Chain Position Source
AF-Q814I2-F1 Predicted AlphaFoldDB

No variants for Q814I2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q814I2

No associated diseases with Q814I2

6 regional properties for Q814I2

Type Name Position InterPro Accession
conserved_site ATP-dependent RNA helicase DEAD-box, conserved site 151 - 159 IPR000629
domain Helicase, C-terminal 230 - 377 IPR001650
domain DEAD box helicase DbpA/CsdA, RNA-binding domain 407 - 477 IPR005580
domain DEAD/DEAH box helicase domain 28 - 194 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 23 - 220 IPR014001
domain RNA helicase, DEAD-box type, Q motif 4 - 32 IPR014014

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

6 GO annotations of molecular function

Name Definition
3'-5' RNA helicase activity Unwinding of an RNA helix in the 3' to 5' direction, driven by ATP hydrolysis.
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.
RNA strand annealing activity An activity that facilitates the formation of a complementary double-stranded RNA molecule.

1 GO annotations of biological process

Name Definition
ribosomal large subunit assembly The aggregation, arrangement and bonding together of constituent RNAs and proteins to form the large ribosomal subunit.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKKSFSDYK LSKEIVRALT GLGYDHPTEV QGEVIPVALQ KKDLVVKSQT GSGKTASFGI
70 80 90 100 110 120
PLCEMVEWEE NKPQALVLTP TRELAVQVKE DITNIGRFKR IKAAAVYGKS PFARQKLELK
130 140 150 160 170 180
QKTHIVVGTP GRVLDHIEKG TLSLECLKYL VIDEADEMLN MGFIDQVEAI IDELPTKRMT
190 200 210 220 230 240
MLFSATLPED VEKLSRTYMN SPTHIEIKAA GITTDKIEHT LFEVIEDEKL SLLKDVTTIE
250 260 270 280 290 300
NPDSCIIFCR TQENVDHVYR QLKRANYPCD KIHGGMVQED RFEVMDDFRK GKFRYLVATD
310 320 330 340 350 360
VAARGIDIDN ITHVINYDIP LEKESYVHRT GRTGRAGNSG KAITFITPYE NRFLEEIEEY
370 380 390 400 410 420
IGFEIPKAIG PSKEEVMKEK AAFEEKLHAK PIIKKDKNAD INKGIMKLYF NGGKKKKIRA
430 440 450 460 470 480
VDFVGTIAKI KGVTAEDIGI ITIQDNVSYV EILNGKGPLV LKVMKTTTIK GKQLKVHEAI
K