Q80UX8
Gene name |
Abhd13 |
Protein name |
Protein ABHD13 |
Names |
Alpha/beta hydrolase domain-containing protein 13, Abhydrolase domain-containing protein 13 |
Species |
Mus musculus (Mouse) |
KEGG Pathway |
mmu:68904 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q80UX8
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q80UX8-F1 | Predicted | AlphaFoldDB |
15 variants for Q80UX8
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| rs3388965885 | 9 | S>I | No | EVA | |
| rs3388969463 | 37 | F>L | No | EVA | |
| rs3388966864 | 67 | F>L | No | EVA | |
| rs3388965646 | 70 | Q>* | No | EVA | |
| rs3388966863 | 74 | S>P | No | EVA | |
| rs3388940015 | 147 | L>F | No | EVA | |
| rs3388962462 | 226 | A>G | No | EVA | |
| rs3388940082 | 226 | A>T | No | EVA | |
| rs3388972866 | 227 | S>I | No | EVA | |
| rs3388970382 | 228 | T>I | No | EVA | |
| rs3388969408 | 249 | S>T | No | EVA | |
| rs3398726772 | 249 | S>Y | No | EVA | |
| rs3398439120 | 250 | Y>D | No | EVA | |
| rs3398544394 | 252 | K>N | No | EVA | |
| rs226757843 | 332 | S>P | No | EVA |
No associated diseases with Q80UX8
1 regional properties for Q80UX8
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Serine aminopeptidase, S33 | 117 - 226 | IPR022742 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| dendrite cytoplasm | All of the contents of a dendrite, excluding the surrounding plasma membrane. |
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| membrane | A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| palmitoyl-(protein) hydrolase activity | Catalysis of the reaction: palmitoyl-protein + H2O = palmitate + protein. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein depalmitoylation | The removal of palymitoyl groups from a lipoprotein. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEKSWMLWSF | IERWLLALAS | WSWALCRISL | LPLIVTFHLY | GGIVLLLLIF | VSIAGILYKF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QDVLLYFPEQ | PSSSRLYVPM | PTGIPHENIF | IRTKDGVRLN | LILVRYTGDN | SPYCPTIIYF |
| 130 | 140 | 150 | 160 | 170 | 180 |
| HGNAGNIGHR | LPNALLMLVN | LRVNLVLVDY | RGYGKSEGEA | SEEGLYLDSE | AVLDYVMTRP |
| 190 | 200 | 210 | 220 | 230 | 240 |
| DLDKTKVFLF | GRSLGGAVAI | HLASENSHRI | SAIMVENTFL | SIPHMASTLF | SFFPMRYLPL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| WCYKNKFLSY | RKISQCRMPS | LFISGLSDQL | IPPVMMKQLY | ELSPSRTKRL | AIFPDGTHND |
| 310 | 320 | 330 | |||
| TWQCQGYFTA | LEQFIKEVIK | SHSPEDMTKT | SSNVTII |