Q80HX6

PR
Gene name
VACWR051 (F12L)
Protein name
Protein F12
Names
Species
Vaccinia virus (strain Western Reserve) (VACV) (Vaccinia virus (strain WR))
KEGG Pathway
vg:3707508
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

319-400 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q80HX6

Entry ID Method Resolution Chain Position Source

No variants for Q80HX6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q80HX6

No associated diseases with Q80HX6

2 regional properties for Q80HX6

Type Name Position InterPro Accession
conserved_site Peptidyl-tRNA hydrolase, conserved site 14 - 27 IPR018171-1
conserved_site Peptidyl-tRNA hydrolase, conserved site 107 - 117 IPR018171-2

Functions

Description
EC Number
Subcellular Localization
  • Virion membrane
  • Host endosome
  • Associates with the membrane of IEV particles, but not intracellular mature virus (IMV), cell-associated enveloped virus (CEV) or EEV
  • Colocalizes with microtubules
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
host cell endosome A membrane-bounded organelle that carries materials newly ingested by endocytosis. It passes many of the materials to host cell lysosomes for degradation.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
virion membrane The lipid bilayer surrounding a virion.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

1 GO annotations of biological process

Name Definition
microtubule-dependent intracellular transport of viral material towards cell periphery The directed movement of the viral genome or a viral particle towards the cell periphery using host microtubules. Mostly used by viruses that replicate their genome near or in the nucleus to allows newly assembled viral progeny to reach the plasma membrane.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLNRVQILMK TANNYETIEI LRNYLRLYII LARNEEGRGI LIYDDNIDSI MSMMNITRLE
70 80 90 100 110 120
VIGLTTHCTK LRSSPPIPMS RLFMDEIDHE SYYSPKTSDY PLIDIIRKRS HEQGDIALAL
130 140 150 160 170 180
EQYGIENTDS ISEINEWLSS KGLACYRFVK FNDYRKQMYR KFSRCTIVDS MIIGHIGHHY
190 200 210 220 230 240
IWIKNLETYT RPEIDVLPFD IKYISRDELW ARISSSLDQT HIKTIAVSVY GAITDNGPMP
250 260 270 280 290 300
YMISTYPGNT FVNFNSVKNL ILNFLDWIKD IMTSTRTIIL VGYMSNLFDI PLLTVYWPNN
310 320 330 340 350 360
CGWKIYNNTL ISSDGARVIW MDAYKFSCGL SLQDYCYHWG SKPESRPFDL IKKSDAKRNS
370 380 390 400 410 420
KSLVKESMAS LKSLYEAFET QSGALEVLMS PCRMFSFSRI EDMFLTSVIN RVSENTGMGM
430 440 450 460 470 480
YYPTNDIPSL FIESSICLDY IIVNNQESNK YRIKSVLDII SSKQYPAGRP NYVKNGTKGK
490 500 510 520 530 540
LYIALCKVTV PTNDHIPVVY HDDDNTTTFI TVLTSVDIET AIRAGYSIVE LGALQWDDNI
550 560 570 580 590 600
PELKHGLLDS IKMIYDLNAV TTNNLLEQLI ENINFNNSSI ISLFYTFAIS YCRAFIYSIM
610 620 630
ETIDPVYISQ FSYKELYVSS SYKDINESMS QMVKL