Q803I2

PR
Gene name
ergic3 (zgc:113959, zgc:55762)
Protein name
Endoplasmic reticulum-Golgi intermediate compartment protein 3
Names
Species
Danio rerio (Zebrafish) (Brachydanio rerio)
KEGG Pathway
dre:393990
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

70-222 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q803I2

Entry ID Method Resolution Chain Position Source
AF-Q803I2-F1 Predicted AlphaFoldDB

No variants for Q803I2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q803I2

No associated diseases with Q803I2

2 regional properties for Q803I2

Type Name Position InterPro Accession
domain Endoplasmic reticulum vesicle transporter, C-terminal 145 - 363 IPR012936
domain Endoplasmic reticulum vesicle transporter, N-terminal 7 - 96 IPR039542

Functions

Description
EC Number
Subcellular Localization
  • Endoplasmic reticulum-Golgi intermediate compartment membrane; Multi-pass membrane protein
  • Golgi apparatus, cis-Golgi network membrane ; Multi-pass membrane protein
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

6 GO annotations of cellular component

Name Definition
COPII-coated ER to Golgi transport vesicle A vesicle with a coat formed of the COPII coat complex proteins. The COPII coat complex is formed by the Sec23p/Sec24p and the Sec13p/Sec31p heterodimers. COPII-associated vesicles transport proteins from the rough endoplasmic reticulum to the Golgi apparatus (anterograde transport).
endoplasmic reticulum The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
endoplasmic reticulum-Golgi intermediate compartment membrane The lipid bilayer surrounding any of the compartments of the endoplasmic reticulum (ER)-Golgi intermediate compartment system.
integral component of endoplasmic reticulum membrane The component of the endoplasmic reticulum membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
integral component of Golgi membrane The component of the Golgi membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
membrane A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

2 GO annotations of biological process

Name Definition
endoplasmic reticulum to Golgi vesicle-mediated transport The directed movement of substances from the endoplasmic reticulum (ER) to the Golgi, mediated by COP II vesicles. Small COP II coated vesicles form from the ER and then fuse directly with the cis-Golgi. Larger structures are transported along microtubules to the cis-Golgi.
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum The directed movement of substances from the Golgi back to the endoplasmic reticulum, mediated by vesicles bearing specific protein coats such as COPI or COG.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MDALNKLKQF DAYPKTLEDF RIKTCGGATV TIISGLIMLI LFFSELQYYL TKEVHPELFV
70 80 90 100 110 120
DTSRGDKLRI NIDVIFPHMP CAYLSIDAMD VAGEQQLDVE HNLFKQRLDK DGQPVTTEAE
130 140 150 160 170 180
KHDLGKEEEG VFDPSTLDPD RCESCYGAET DDLKCCNTCD DVREAYRRRG WAFKTPDTIE
190 200 210 220 230 240
QCKREGFSQK MQEQKNEGCQ VYGFLEVNKV AGNFHFAPGK SFQQSHVHVH DLQSFGLDNI
250 260 270 280 290 300
NMTHFIKHLS FGKDYPGIVN PLDDTNVAAP QASMMYQYFV KIVPTIYVKG DGEVVKTNQF
310 320 330 340 350 360
SVTRHEKIAN GLIGDQGLPG VFVLYELSPM MVKFTEKQRS FTHFLTGVCA IIGGVFTVAG
370 380
LIDSLIYHSA RAIQKKIELG KAS