Q7ZYA2

PR
Gene name
taf8
Protein name
Transcription initiation factor TFIID subunit 8
Names
TBP-associated factor 8
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:380201
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-293 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7ZYA2

Entry ID Method Resolution Chain Position Source
AF-Q7ZYA2-F1 Predicted AlphaFoldDB

No variants for Q7ZYA2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7ZYA2

No associated diseases with Q7ZYA2

2 regional properties for Q7ZYA2

Type Name Position InterPro Accession
domain Bromodomain associated domain 19 - 96 IPR006565
domain Transcription factor TFIID, subunit 8, C-terminal 134 - 187 IPR019473

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
transcription factor TFIID complex A complex composed of TATA binding protein (TBP) and TBP associated factors (TAFs); the total mass is typically about 800 kDa. Most of the TAFs are conserved across species. In TATA-containing promoters for RNA polymerase II (Pol II), TFIID is believed to recognize at least two distinct elements, the TATA element and a downstream promoter element. TFIID is also involved in recognition of TATA-less Pol II promoters. Binding of TFIID to DNA is necessary but not sufficient for transcription initiation from most RNA polymerase II promoters.

1 GO annotations of molecular function

Name Definition
protein heterodimerization activity Binding to a nonidentical protein to form a heterodimer.

1 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MFPTIRSCAR GTSTPADNYM LARRRTLQVV VSSLLTEAGF DSAEKAAVES LTEMLQSYLS
70 80 90 100 110 120
EIGRSAKSYC EHTARTQPTL PDIVVTLIEM GFNVDSLPAY AKRSQRMVIT APPVTNNPVV
130 140 150 160 170 180
PKALSAGDNK PHPAHIPSHF PEFPDPHTYI KTPTYREPVC DYQVLREKAA SQRRDVERAL
190 200 210 220 230 240
TRFMAKTGET QSLFKDDTST FPLIAARPLS IPYLNALLPS ELELQQVDET DSSEQDDQTD
250 260 270 280 290
TENLSLHLQG DEVGMEKENA SVLQQNSMKG GEETLIDNPY LRPVKKPKLR RKK