Q7ZX64
Gene name |
ppp2r2d |
Protein name |
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform |
Names |
PP2A subunit B isoform B55-delta, PP2A subunit B isoform PR55-delta, PP2A subunit B isoform R2-delta, PP2A subunit B isoform delta |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:379305 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7ZX64
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7ZX64-F1 | Predicted | AlphaFoldDB |
No variants for Q7ZX64
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7ZX64 | |||||
No associated diseases with Q7ZX64
9 regional properties for Q7ZX64
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 14 - 56 | IPR001680-1 |
| repeat | WD40 repeat | 83 - 123 | IPR001680-2 |
| repeat | WD40 repeat | 165 - 204 | IPR001680-3 |
| repeat | WD40 repeat | 215 - 255 | IPR001680-4 |
| repeat | WD40 repeat | 274 - 312 | IPR001680-5 |
| repeat | WD40 repeat | 339 - 370 | IPR001680-6 |
| repeat | WD40 repeat | 406 - 443 | IPR001680-7 |
| conserved_site | Protein phosphatase 2A regulatory subunit PR55, conserved site | 83 - 97 | IPR018067-1 |
| conserved_site | Protein phosphatase 2A regulatory subunit PR55, conserved site | 174 - 188 | IPR018067-2 |
3 GO annotations of cellular component
| Name | Definition |
|---|---|
| cytoplasm | The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
| nucleoplasm | That part of the nuclear content other than the chromosomes or the nucleolus. |
| protein phosphatase type 2A complex | A protein complex that has protein serine/threonine phosphatase activity that is polycation-stimulated (PCS), being directly stimulated by protamine, polylysine, or histone H1; it constitutes a subclass of several enzymes activated by different histones and polylysine, and consists of catalytic, scaffolding, and regulatory subunits. The catalytic and scaffolding subunits form the core enzyme, and the holoenzyme also includes the regulatory subunit. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein phosphatase regulator activity | Binds to and modulates the activity of a protein phosphatase, an enzyme which catalyzes of the removal of a phosphate group from a protein substrate molecule. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| cell division | The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells. |
| exit from mitosis | The cell cycle transition where a cell leaves M phase and enters a new G1 phase. M phase is the part of the mitotic cell cycle during which mitosis and cytokinesis take place. |
| mitotic cell cycle | Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MAGVGGGNDF | QWCFSQVKGA | IDEDVAEADI | ISTVEFNCSG | ELLATGDKGG | RVVIFQREQE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NKSRPHSRGE | YNVYSTFQSH | EPEFDYLKSL | EIEEKINKIR | WLPQQNAANF | LLSTNDKTIK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LWKISERDKR | VEGYNLKDDD | GRLRDPFRIT | SLRVPILKPM | DLMVEASPRR | IFANAHTYHI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| NSISVNSDHQ | TYLSADDLRV | NLWHLEITDR | SFNIVDIKPA | NMEELTEVIT | AAEFHPHHCH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| MFVYSSSKGT | IRLCDMRDAA | LCDRHSKFFE | EPEDPSSRSF | FSEIISSISD | VKFSHSGRYM |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MTRDYLSVKV | WDLNMESRPV | ETYQVHEYLR | SKLCSLYEND | CIFDKFECCW | NGSDSSIMTG |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SYNNFFRMFD | RNTRRDITLE | ASRESSKPRA | TLKPRKVCTG | GKRKKDEINV | DSLDFNKKIL |
| 430 | 440 | ||||
| HTAWHPTDNI | IAVAATNNLY | IFQDKVN |