Q7ZX31
Gene name |
ing3 |
Protein name |
Inhibitor of growth protein 3 |
Names |
|
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:379972 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7ZX31
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7ZX31-F1 | Predicted | AlphaFoldDB |
No variants for Q7ZX31
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7ZX31 | |||||
No associated diseases with Q7ZX31
5 regional properties for Q7ZX31
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Zinc finger, PHD-type | 360 - 405 | IPR001965 |
| conserved_site | Zinc finger, PHD-type, conserved site | 361 - 404 | IPR019786 |
| domain | Zinc finger, PHD-finger | 358 - 407 | IPR019787 |
| domain | Inhibitor of growth protein, N-terminal histone-binding | 3 - 104 | IPR024610 |
| domain | ING3, PHD domain | 360 - 404 | IPR042020 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| Swr1 complex | A multisubunit protein complex that is involved in chromatin remodeling. It is required for the incorporation of the histone variant H2AZ into chromatin. In S. cerevisiae, the complex contains Swr1p, a Swi2/Snf2-related ATPase, and 12 additional subunits. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
4 GO annotations of biological process
| Name | Definition |
|---|---|
| chromatin organization | The assembly or remodeling of chromatin composed of DNA complexed with histones, other associated proteins, and sometimes RNA. |
| histone H2A acetylation | The modification of histone H2A by the addition of an acetyl group. |
| histone H4 acetylation | The modification of histone H4 by the addition of an acetyl group. |
| positive regulation of apoptotic process | Any process that activates or increases the frequency, rate or extent of cell death by apoptotic process. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MLYLEDYLEM | IEQLPMDLRD | RFTEMREMDL | QVQNAMDQLE | QRVGEFFMNA | KKNKPEWREE |
| 70 | 80 | 90 | 100 | 110 | 120 |
| QMASIKKDYF | KALEDADEKV | QLANQIYDLV | DRHLRKLDQE | LAKFKMELEA | DNAGITEILE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| RRSLELDTPS | QPVNNHHVHS | HSSGEKRKHI | PSSHHSTTDH | VPEKKFKSEA | LLSTLTSDAS |
| 190 | 200 | 210 | 220 | 230 | 240 |
| KENTAGCRTN | LSSSSTNNVY | NVNSSQPLTS | YNISSLSTGA | AAGAITMAAA | QAVQATAQMK |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EGRRTSSLKA | SYEAFKNTDL | LGISLSRDSA | SYSSSALAST | LTQTLTSSAT | TDSRSGRKSK |
| 310 | 320 | 330 | 340 | 350 | 360 |
| SNNKSASQQS | SSSSSSSSLS | SCSSSSALAH | ELSHQQTAAI | PESDTNSQVD | WTYDPNEPRY |
| 370 | 380 | 390 | 400 | 410 | |
| CICNQVSYGE | MVGCDNQDCP | IEWFHYGCVG | LSEAPKGKWY | CPQCTAAMKR | RGSRHK |