Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7ZV50

Entry ID Method Resolution Chain Position Source
AF-Q7ZV50-F1 Predicted AlphaFoldDB

No variants for Q7ZV50

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7ZV50

No associated diseases with Q7ZV50

3 regional properties for Q7ZV50

Type Name Position InterPro Accession
conserved_site Translation initiation factor 3, conserved site 62 - 75 IPR019813
domain Translation initiation factor 3, N-terminal 11 - 79 IPR019814
domain Translation initiation factor 3, C-terminal 87 - 171 IPR019815

Functions

Description
EC Number
Subcellular Localization
  • Cell membrane ; Multi-pass membrane protein
  • Endoplasmic reticulum
  • Endoplasmic reticulum membrane ; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

3 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
oligosaccharyltransferase complex A protein complex that is found in the endoplasmic reticulum membrane of eukaryotes and transfers lipid-linked oligosaccharide precursor to asparagine residues on nascent proteins. In yeast, the complex includes at least nine different subunits, whereas in mammalian cells at least three different forms of the complex have been detected.
plasma membrane The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

1 GO annotations of molecular function

Name Definition
magnesium ion transmembrane transporter activity Enables the transfer of magnesium (Mg) ions from one side of a membrane to the other.

2 GO annotations of biological process

Name Definition
magnesium ion transport The directed movement of magnesium (Mg) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
protein N-linked glycosylation A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLHKLLIVVF LVVCLHDMRL NGQKKKETLL SEKVSQMMEW VSKRAVVRLN GEKFKRLVRA
70 80 90 100 110 120
HPRNYSVIVM FTALQPQRQC GVCRQADEEY QILANSWRYS SAFTNRIFFA MVDFDEGSDV
130 140 150 160 170 180
FQMLNMNSAP TFINFPAKGK PKRADTYELQ VRGFAAEQLA RWVADRTDVH IRVIRPPNYA
190 200 210 220 230 240
GPLMLGLLLA FIGSLAYLRR NNLEFLFNKN VWAFSALCFV LIMTSGQMWN HIRGPPYAHK
250 260 270 280 290 300
NPNTGQVSYI HGSSQAQFVA ETHIVLLFNA AVTIGMVLLH EAATSGLDIV KRKIMCVAGI
310 320
GLVVLFFSWL LSVFRAKYHG YPYSFLFG