Q7ZA45
Gene name |
GPD |
Protein name |
Glycerol-3-phosphate dehydrogenase [NAD(+)] |
Names |
|
Species |
Lachancea thermotolerans (Yeast) (Kluyveromyces thermotolerans) |
KEGG Pathway |
|
EC number |
1.1.1.8: With NAD(+) or NADP(+) as acceptor |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7ZA45
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7ZA45-F1 | Predicted | AlphaFoldDB |
No variants for Q7ZA45
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7ZA45 | |||||
No associated diseases with Q7ZA45
Functions
| Description | ||
|---|---|---|
| EC Number | 1.1.1.8 | With NAD(+) or NADP(+) as acceptor |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| glycerol-3-phosphate dehydrogenase complex | An enzyme complex that catalyzes the dehydrogenation of sn-glycerol 3-phosphate to form glycerone phosphate. |
3 GO annotations of molecular function
| Name | Definition |
|---|---|
| glycerol-3-phosphate dehydrogenase [NAD+] activity | Catalysis of the reaction: sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH + H+. |
| NAD binding | Binding to nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. |
| protein homodimerization activity | Binding to an identical protein to form a homodimer. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| carbohydrate metabolic process | The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. |
| glycerol-3-phosphate catabolic process | The chemical reactions and pathways resulting in the breakdown of glycerol-3-phosphate, a phosphoric monoester of glycerol. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MFSISRITRT | SSFTTQFRAL | YRFKHSARKL | QSIPFSIYKK | MSAADRLNQT | HDILSESVQA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| VENPFKVTVI | GSGNWGTTIS | KVVAENAALR | PHLFVKRVDM | WVFEETVDGQ | KLTEIINTKH |
| 130 | 140 | 150 | 160 | 170 | 180 |
| QNVKYLPNID | LPENLVANPD | LVSAVKDADI | LVFNIPHQFL | PRIVSQLQGN | IKKDARAISC |
| 190 | 200 | 210 | 220 | 230 | 240 |
| LKGFDVSKDG | VKLLSTYVTE | KLGITCGALS | GANLAPEVAK | ENWSETTVAY | ELPKDFKGEG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| KDVDHAVLKA | LFHRPYFHVN | VIDDVAGISV | AGALKNVVAL | GCGFVEGLGW | GNNASAAIQR |
| 310 | 320 | 330 | 340 | 350 | 360 |
| VGLGEIIKFG | QMFFPDSRVE | TYYQESAGVA | DLITTCSGGR | NVRVATHMAK | TGKSAEECEK |
| 370 | 380 | 390 | 400 | 410 | |
| ELLNGQSAQV | FTHVRRSTSG | WPSAVRPMNS | FCSRPFTRLS | TRTLLWTLCQ | T |