Q7Y1W1
Gene name |
TIC56 |
Protein name |
Protein TIC 56, chloroplastic |
Names |
Translocon at the inner envelope membrane of chloroplasts 56, AtTIC56 |
Species |
Arabidopsis thaliana (Mouse-ear cress) |
KEGG Pathway |
ath:AT5G01590 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7Y1W1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7Y1W1-F1 | Predicted | AlphaFoldDB |
31 variants for Q7Y1W1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| tmp_5_224264_T_A | 6 | F>I | No | 1000Genomes | |
| tmp_5_224271_C_T | 8 | P>L | No | 1000Genomes | |
| tmp_5_224297_C_G | 17 | P>A | No | 1000Genomes | |
| ENSVATH10482848 | 61 | T>I | No | 1000Genomes | |
| ENSVATH06903857 | 73 | Q>H | No | 1000Genomes | |
| ENSVATH00600052 | 93 | L>F | No | 1000Genomes | |
| ENSVATH00600052 | 93 | L>I | No | 1000Genomes | |
| tmp_5_224543_G_T | 99 | V>F | No | 1000Genomes | |
| tmp_5_224657_G_T | 137 | A>S | No | 1000Genomes | |
| tmp_5_224660_G_A | 138 | D>N | No | 1000Genomes | |
| ENSVATH06903858 | 149 | D>N | No | 1000Genomes | |
| tmp_5_224721_A_G | 158 | D>G | No | 1000Genomes | |
| ENSVATH13871010 | 169 | F>L | No | 1000Genomes | |
| ENSVATH13871011 | 224 | R>W | No | 1000Genomes | |
| tmp_5_224926_G_T | 226 | E>D | No | 1000Genomes | |
| tmp_5_225531_G_A | 274 | G>S | No | 1000Genomes | |
| ENSVATH00600060 | 291 | P>S | No | 1000Genomes | |
| ENSVATH06903866 | 299 | R>K | No | 1000Genomes | |
| ENSVATH13871115 | 303 | A>V | No | 1000Genomes | |
| ENSVATH10482944 | 306 | A>T | No | 1000Genomes | |
| ENSVATH03003631 | 306 | A>V | No | 1000Genomes | |
| ENSVATH03003636 | 325 | E>G | No | 1000Genomes | |
| tmp_5_225832_A_T | 334 | K>N | No | 1000Genomes | |
| ENSVATH13871117 | 348 | E>D | No | 1000Genomes | |
| ENSVATH06903867 | 362 | H>Y | No | 1000Genomes | |
| ENSVATH10482976 | 421 | G>E | No | 1000Genomes | |
| tmp_5_226552_G_A | 506 | G>S | No | 1000Genomes | |
| ENSVATH06903872 | 517 | E>D | No | 1000Genomes | |
| ENSVATH03003643 | 518 | E>D | No | 1000Genomes | |
| tmp_5_226609_A_C | 525 | K>Q | No | 1000Genomes | |
| ENSVATH06903873 | 525 | K>T | No | 1000Genomes |
No associated diseases with Q7Y1W1
1 regional properties for Q7Y1W1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Proteasome component (PCI) domain | 298 - 509 | IPR000717 |
5 GO annotations of cellular component
| Name | Definition |
|---|---|
| chloroplast | A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
| chloroplast envelope | The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. |
| chloroplast inner membrane | The inner, i.e. lumen-facing, lipid bilayer of the chloroplast envelope; also faces the chloroplast stroma. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
| plastid | Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| protein transmembrane transporter activity | Enables the transfer of a protein from one side of a membrane to the other. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| protein import into chloroplast stroma | The targeting and import of proteins into the chloroplast stroma. Import depends on ATP hydrolysis catalyzed by stromal chaperones. Chloroplast stromal proteins, such as the S subunit of rubisco, have a N-terminal stromal-import sequence of about 44 amino acids which is cleaved from the protein precursor after import. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSSMNFNPFQ | NWFEKPPNPV | PSINFVSLAD | SFFPKSQSPN | FASIGLPKFS | KKSPKPETAG |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TDEPGPYKQI | AEQFLWECEN | IPDYRHTPEV | DKLLNEDPVF | EKKENPSTEE | IEAEQKWWES |
| 130 | 140 | 150 | 160 | 170 | 180 |
| FRASPVVQFM | TRAEEIADDM | NKMELEDNDT | PYRKEDKDYW | RAIPHVPGFD | GRPMPRKAIK |
| 190 | 200 | 210 | 220 | 230 | 240 |
| SKEESDDKFW | DFMKQFLFGL | WGFRQRPYPP | GRPIDVAQAI | GYKRLEKRYY | DFIMKTGGWW |
| 250 | 260 | 270 | 280 | 290 | 300 |
| YKDRLGRSRG | PCEIITLKTA | YGAGIIDRDT | FIWGEDMDEW | APIHMVYGLE | PAIATWEVRL |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GAAATAFLHK | LQKGIPPWVP | LKGREPKTYK | QLQKEAIESK | KRDMAVLEAN | GGVWPGVRTP |
| 370 | 380 | 390 | 400 | 410 | 420 |
| SHALFLWASG | SELTTVLESD | HMPNKFIPKQ | LRLELAKVIP | GLRPWEVISI | EQAMDQISYG |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GEWYREPLGT | YTTGPPYIRE | WNRSVMRLFR | IFYNLSVRVG | QKLERTVPGF | DTIMDKVQKD |
| 490 | 500 | 510 | 520 | ||
| YDKRIARRMK | RREEELREED | LKHYSGRTDE | DEEEEEEEDD | DSNSKKD |