Q7WTJ2
Gene name |
mphP (BDGL_000470) |
Protein name |
Phenol hydroxylase P5 protein |
Names |
Phenol 2-monooxygenase P5 component |
Species |
Acinetobacter calcoaceticus (strain PHEA-2) |
KEGG Pathway |
acc:BDGL_000470 |
EC number |
1.14.13.7: With NADH or NADPH as one donor, and incorporation of one atom of oxygen |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7WTJ2
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7WTJ2-F1 | Predicted | AlphaFoldDB |
No variants for Q7WTJ2
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7WTJ2 | |||||
No associated diseases with Q7WTJ2
5 regional properties for Q7WTJ2
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | 2Fe-2S ferredoxin-type iron-sulfur binding domain | 3 - 93 | IPR001041 |
| domain | Oxidoreductase FAD/NAD(P)-binding | 210 - 314 | IPR001433 |
| binding_site | 2Fe-2S ferredoxin, iron-sulphur binding site | 37 - 45 | IPR006058 |
| domain | Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain | 107 - 198 | IPR008333 |
| domain | FAD-binding domain, ferredoxin reductase-type | 102 - 201 | IPR017927 |
Functions
| Description | ||
|---|---|---|
| EC Number | 1.14.13.7 | With NADH or NADPH as one donor, and incorporation of one atom of oxygen |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
4 GO annotations of molecular function
| Name | Definition |
|---|---|
| 2 iron, 2 sulfur cluster binding | Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands. |
| flavin adenine dinucleotide binding | Binding to FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2. |
| metal ion binding | Binding to a metal ion. |
| phenol 2-monooxygenase activity | Catalysis of the reaction: phenol + NADPH + H+ + O2 = catechol + NADP+ + H2O. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| aerobic phenol-containing compound catabolic process | The chemical reactions and pathways resulting in the breakdown of a phenol, any compound containing one or more hydroxyl groups directly attached to an aromatic carbon ring, in the presence of oxygen. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSYQVTIEPI | GTTIEVEEDQ | TILDAALRQG | VWLPFACGHG | TCGTCKVQVT | DGFYDVGEAS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| PFALMDIERD | ENKVLACCCK | PQSDMVIEAD | VDEDPDFLGH | LVQDYQATVI | EIKDLSPTIK |
| 130 | 140 | 150 | 160 | 170 | 180 |
| GIRLQLDRPI | EFQAGQYINV | QFPNIEGTRA | FSIANSPSEV | GIVELHIRKV | EGGAATTYVH |
| 190 | 200 | 210 | 220 | 230 | 240 |
| EQLATGDQLD | ISGPYGQFFV | RKSDDQNAIF | IAGGSGLSSP | QSMILDLLES | GDSRTIYLFQ |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GARDLAELYN | RELFEQLVKD | YPNFRYIPAL | NAPKPEDQWT | GFTGFVHEAV | ADYFENRCGG |
| 310 | 320 | 330 | 340 | 350 | |
| HKAYLCGPPI | MIDSAISTLM | QSRLFERDIH | TERFLSAADG | AAGQSRSALF | KHI |