Q7W9E6

PR
Gene name
clpB (BPP1814)
Protein name
Chaperone protein ClpB
Names
Species
Bordetella parapertussis (strain 12822 / ATCC BAA-587 / NCTC 13253)
KEGG Pathway
bpa:BPP1814
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

110-195 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7W9E6

Entry ID Method Resolution Chain Position Source
AF-Q7W9E6-F1 Predicted AlphaFoldDB

No variants for Q7W9E6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7W9E6

No associated diseases with Q7W9E6

9 regional properties for Q7W9E6

Type Name Position InterPro Accession
domain AAA+ ATPase domain 197 - 343 IPR003593-1
domain AAA+ ATPase domain 603 - 768 IPR003593-2
domain ATPase, AAA-type, core 202 - 334 IPR003959-1
domain ATPase, AAA-type, core 602 - 765 IPR003959-2
domain Clp, repeat (R) domain 3 - 145 IPR004176
conserved_site ClpA/B, conserved site 1 293 - 305 IPR018368
domain Clp ATPase, C-terminal 771 - 860 IPR019489
conserved_site ClpA/B, conserved site 2 637 - 655 IPR028299
domain ClpA/ClpB, AAA lid domain 342 - 441 IPR041546

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.

2 GO annotations of biological process

Name Definition
protein refolding The process carried out by a cell that restores the biological activity of an unfolded or misfolded protein, using helper proteins such as chaperones.
response to heat Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MRFDKLTTKF QQALADAQSL AARNDHPYIE PVHVLAALLG DPDSGAASLL ARAGVAVNRV
70 80 90 100 110 120
QPAIDSALKG LPQVQGEDNV QVGRELQSVL VRTDKEAARR GDTYIASELF LLALADDKGD
130 140 150 160 170 180
AGRILREAGL QKKALEAAID AVRGGENVSG AEGESNREAL SKYTLDLTER ARQGKLDPVI
190 200 210 220 230 240
GRDDEIRRTI QILQRRTKNN PVLIGEPGVG KTAIVEGLAQ RIVNDEVPET LRGKRVLSLD
250 260 270 280 290 300
LAALLAGAKF RGEFEERLKA VLKELAQDDG QNIVFIDELH TMVGAGKAEG AMDAGNMLKP
310 320 330 340 350 360
ALARGELHCI GATTLDEYRK YIEKDAALER RFQKVLVGEP DVESTIAILR GLQERYELHH
370 380 390 400 410 420
GVEITDPAIV AAAELSHRYI TDRFLPDKAI DLIDEAGARI RMEIDSKPEV MDRLDRRIIQ
430 440 450 460 470 480
LKIEREAVKK ETDDASMRRL AVIEEELEKL QREYNDYEEI WKAEKAAVQG TQAIKEEIDR
490 500 510 520 530 540
VRAEMAELQR KGQFDKLAEL QYGKLPELEA RLKAADSAER EAGESDSGKP RLLRTQVGAE
550 560 570 580 590 600
EIAEVVSRAT GIPVAKMMQG ERDKLLRMED FLHKRVVGQD EAVRLVSDAI RRSRAGLADP
610 620 630 640 650 660
SRPYGSFLFL GPTGVGKTEL TRALADFLFD SEEHMIRIDM SEFMEKHSVA RLIGAPPGYV
670 680 690 700 710 720
GYEEGGYLTE AVRRKPYSVI LLDEVEKAHP DVFNVLLQVL DDGRLTDGQG RTVDFRNTVI
730 740 750 760 770 780
VMTSNLGSQH IQSMAGKPYE VIKEVVWDEL KHTFRPEFLN RIDEVVVFHG LEAQHIESIA
790 800 810 820 830 840
RIQLKRLGER LEKQEMRLDV SDAALAEIAR SGFDPVFGAR PLKRAVQQQI ENPVAKLILE
850 860
GVFGPRDVVP VDWQDGKFVF TRTLQ