Q7VSZ0
Gene name |
hisC2 (BP3769) |
Protein name |
Histidinol-phosphate aminotransferase 2 |
Names |
Imidazole acetol-phosphate transaminase 2 |
Species |
Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) |
KEGG Pathway |
bpe:BP3769 |
EC number |
2.6.1.9: Transaminases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7VSZ0
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7VSZ0-F1 | Predicted | AlphaFoldDB |
No variants for Q7VSZ0
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7VSZ0 | |||||
No associated diseases with Q7VSZ0
1 regional properties for Q7VSZ0
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | Histidinol dehydrogenase, conserved site | 235 - 267 | IPR001692 |
Functions
| Description | ||
|---|---|---|
| EC Number | 2.6.1.9 | Transaminases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| histidinol-phosphate transaminase activity | Catalysis of the reaction: L-histidinol-phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate. |
| pyridoxal phosphate binding | Binding to pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| histidine biosynthetic process | The chemical reactions and pathways resulting in the formation of histidine, 2-amino-3-(1H-imidazol-4-yl)propanoic acid. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MTGVAAPERI | ARAVRADIRA | LTAYPVADAA | GCIKLDAMEC | PYELPAEVRD | DIARAARETP |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LNRYPAAANP | ALQAQVRQAF | EVPAQAGLLF | GNGSDELIHL | IIQACCEPGD | TVLSPWPSFV |
| 130 | 140 | 150 | 160 | 170 | 180 |
| YFDMAARLSH | ARFVGVPLTA | GLELDLPATL | AAIEAHQPKV | VFLALPNNPT | GDLWPDAAVR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AILDAAPGLV | VLDEAYQPFA | GHTWMPRIMD | EPNAVVMRTV | SKIGLAGLRF | GYLAGHPAWI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| AEFDKVRPPY | NMDVLSQAVL | AAVLRHKPVL | DAQADRLRAD | RQPLADGLAA | LPGVTVFPSA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| GNFVLARFCG | KLDGNAVHLA | PKTRKILVRN | FSNAHPLLAD | CLRISVGTPT | ENAAVLSALQ |
| DILSA |