Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

Autoinhibited structure

Activated structure

1 structures for Q7VPN8

Entry ID Method Resolution Chain Position Source
AF-Q7VPN8-F1 Predicted AlphaFoldDB

No variants for Q7VPN8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7VPN8

No associated diseases with Q7VPN8

3 regional properties for Q7VPN8

Type Name Position InterPro Accession
domain Integrase, catalytic domain 107 - 291 IPR002104
domain Integrase, SAM-like, N-terminal 8 - 89 IPR004107
domain Core-binding (CB) domain 2 - 86 IPR044068

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
tyrosine-based site-specific recombinase activity Catalysis of the formation of new phosphodiester bonds between a pair of short, unique DNA target sequences; occurs through a phosphotyrosyl intermediate in which the target sequence is first cleaved by the nucleophilic attack by a tyrosine in the active site.

4 GO annotations of biological process

Name Definition
cell cycle The progression of biochemical and morphological phases and events that occur in a cell during successive cell replication or nuclear replication events. Canonically, the cell cycle comprises the replication and segregation of genetic material followed by the division of the cell, but in endocycles or syncytial cells nuclear replication or nuclear division may not be followed by cell division.
cell division The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
chromosome segregation The process in which genetic material, in the form of chromosomes, is organized into specific structures and then physically separated and apportioned to two or more sets. In eukaryotes, chromosome segregation begins with the condensation of chromosomes, includes chromosome separation, and ends when chromosomes have completed movement to the spindle poles.
transposition, DNA-mediated Any process involved in a type of transpositional recombination which occurs via a DNA intermediate.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MKKLDPIIEQ FLDTLWLEQS LSHNTLLSYR LDLELFSAWL VEPRAFLTLT HTDLQLFLGD
70 80 90 100 110 120
RLDKGYKSSS SARIISCLRK FFRFLCLEKY RLDDPTSMLI SPRKRVQLPK SLSEEQVMDL
130 140 150 160 170 180
LDAPNPLDPI ELRDKAMLEL LYATGLRVTE LISLTIDNLN LRQGVVRVIG KGDKERLVPI
190 200 210 220 230 240
GEEASYWIQE FFDYGRMILL SDQQSDVLFP SRRAKQMTRQ TFWHRIKYYA ILAGIDAEKL
250 260 270 280 290
SPHVLRHAFA THLINHGADL RVVQMLLGHS DLSTTQIYTH VAKTRLKSIH KQFHPRG