Q7V8V2

PR
Gene name
queA
Protein name
S-adenosylmethionine:tRNA ribosyltransferase-isomerase
Names
Queuosine biosynthesis protein QueA
Species
Prochlorococcus marinus (strain MIT 9313)
KEGG Pathway
pmt:PMT_0223
EC number
2.4.99.17: Transferring other glycosyl groups
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-69 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7V8V2

Entry ID Method Resolution Chain Position Source
AF-Q7V8V2-F1 Predicted AlphaFoldDB

No variants for Q7V8V2

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7V8V2

No associated diseases with Q7V8V2

No regional properties for Q7V8V2

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q7V8V2

Functions

Description
EC Number 2.4.99.17 Transferring other glycosyl groups
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

1 GO annotations of molecular function

Name Definition
S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity Catalysis of the reaction: S-adenosylmethionine + 7-(aminomethyl)-7-deazaguanosine-tRNA = adenine + methionine + epoxyqueuosine-tRNA. 7-(aminomethyl)-7-deazaguanosine-tRNA is also known as preQ1-tRNA, and epoxyqueuosine-tRNA as oQ-tRNA.

1 GO annotations of biological process

Name Definition
queuosine biosynthetic process The chemical reactions and pathways resulting in the formation of queuosines, a series of nucleosides found in tRNA and having an additional pentenyl ring added via an NH group to the methyl group of 7-methylguanosine. The pentenyl ring may carry other substituents.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MVLDPRDSLL SSYDYPLDPE RIAQLPVEPR HSARLLIVQP LGMKPPIARH AEVWDWQEEL
70 80 90 100 110 120
RAGDLLVIND TRVLKARLRV RRSGGGLAEL LVLEPRGEGC WLCLGRPAKR LRPGDQLWLE
130 140 150 160 170 180
ALGEEPIALQ VISKDSASGG RVVQFPSHYA NAEQLELLLE RYGEVPLPPY IQRHDPSDSE
190 200 210 220 230 240
RYQTRYASRP GAVAAPTAGL HLSDELLEAL KQRGVMLTSV TLHVGLGTFR PVETEDLSHL
250 260 270 280 290 300
QLHSEWVEVR DDVVEAVMAC RARAGRVIAV GTTSVRALEG AALAGGGFLQ SFCGPVDLVI
310 320 330 340 350 360
QPGYRFAVVD GLLTNFHLPK SSLLLLVSAM VGRERLLALY AEAIEHQYRF FSYGDAMWID
370
PEAVLPAARP C