Q7V051

PR
Gene name
gpmI
Protein name
2,3-bisphosphoglycerate-independent phosphoglycerate mutase
Names
BPG-independent PGAM, Phosphoglyceromutase, iPGM
Species
Prochlorococcus marinus subsp. pastoris (strain CCMP1986 / NIES-2087 / MED4)
KEGG Pathway
pmm:PMM1434
EC number
5.4.2.12: Phosphotransferases (phosphomutases)
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-43 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7V051

Entry ID Method Resolution Chain Position Source
AF-Q7V051-F1 Predicted AlphaFoldDB

No variants for Q7V051

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7V051

No associated diseases with Q7V051

2 regional properties for Q7V051

Type Name Position InterPro Accession
domain Metalloenzyme 18 - 513 IPR006124
domain BPG-independent PGAM, N-terminal 95 - 305 IPR011258

Functions

Description
EC Number 5.4.2.12 Phosphotransferases (phosphomutases)
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

2 GO annotations of molecular function

Name Definition
2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity Catalysis of the reaction: 2-phospho-D-glycerate = 3-phospho-D glycerate; this reaction does not require the cofactor 2,3-bisphosphoglycerate.
manganese ion binding Binding to a manganese ion (Mn).

2 GO annotations of biological process

Name Definition
glucose catabolic process The chemical reactions and pathways resulting in the breakdown of glucose, the aldohexose gluco-hexose.
glycolytic process The chemical reactions and pathways resulting in the breakdown of a carbohydrate into pyruvate, with the concomitant production of a small amount of ATP and the reduction of NAD(P) to NAD(P)H. Glycolysis begins with the metabolism of a carbohydrate to generate products that can enter the pathway and ends with the production of pyruvate. Pyruvate may be converted to acetyl-coenzyme A, ethanol, lactate, or other small molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSKFSSKNIN KTKVPESPVV LAILDGWGHR EENLDNAIKN ANTPIMDSLW HAYPHTLINA
70 80 90 100 110 120
SGADVGLPNG QMGNSEVGHL TIGSGRIIQQ ELVRITNVVK NNQLTQVNEL KEMANSIKKK
130 140 150 160 170 180
KGTLHITGLC SDGGVHSHID HLLGLIKWAS EEHIEKVAIH IITDGRDTPA KSAYKYIRQI
190 200 210 220 230 240
EDCIKKFKVG EIASICGRYW IMDRNLIWER TEKAFVNLTD PNGKKIDISP ADYLNKSYNA
250 260 270 280 290 300
NITDEFLEPI RISKDFLKDE DSLICFNFRP DRARQIIKAL SEKEFDNFKR KSIPDVDILT
310 320 330 340 350 360
FTQYEANLPV KIAFPPESLN NFIGQIVSEN GLKQYRTAET EKYPHVTYFF NGGVEVPSPG
370 380 390 400 410 420
EQRHLIPSPR VATYDMAPEM SAEELTISCS NAIKTGQYSF VVINFANPDM VGHTGNMAAA
430 440 450 460 470 480
IKAIETVDRC IGKIVNATGE MGGSILITAD HGNAELMKGP DGEPWTAHTI NKVPLIFIEG
490 500 510 520 530
EKRKIPNMGN EIYLRENAGL ADIAPTLLQL LNLPIPKEMT GKSLIKEIEL KGFNKVVQHV