Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7TX22
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7TX22-F1 | Predicted | AlphaFoldDB |
No variants for Q7TX22
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7TX22 | |||||
No associated diseases with Q7TX22
6 regional properties for Q7TX22
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Apoptosis regulator, Bcl-2 protein, BH4 | 1 - 27 | IPR003093 |
| conserved_site | Apoptosis regulator, Bcl-2, BH1 motif, conserved site | 130 - 148 | IPR020717 |
| conserved_site | Apoptosis regulator, Bcl-2, BH2 motif, conserved site | 181 - 192 | IPR020726 |
| conserved_site | Apoptosis regulator, Bcl-2, BH3 motif, conserved site | 86 - 100 | IPR020728 |
| conserved_site | Apoptosis regulator, Bcl-2, BH4 motif, conserved site | 4 - 24 | IPR020731 |
| domain | Bcl-2, Bcl-2 homology region 1-3 | 90 - 188 | IPR046371 |
2 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
No GO annotations of molecular function
| Name | Definition |
|---|---|
| No GO annotations for molecular function |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MGMRSAARMP | KLTRRSRILI | MIALGVIVLL | LAGPRLIDAY | VDWLWFGELG | YRSVFTTMLA |
| 70 | 80 | 90 | 100 | 110 | 120 |
| TRIVVCLVAG | VVVGGIVFGG | LALAYRTRPV | FVPDADNDPV | ARYRAVVLAR | LRLVGIGIPA |
| 130 | 140 | 150 | 160 | 170 | 180 |
| AIGLLAGIVA | QSYWARIQLF | LHGGDFGVRD | PQFGRDLGFY | AFELPFYRLM | LSYMLVSVFL |
| 190 | 200 | 210 | 220 | 230 | 240 |
| AFVANLVAHY | IFGGIRLSGR | TGALSRSARV | QLVSLVGVLV | LLKAVAYWLD | RYELLSHTRG |
| 250 | 260 | 270 | 280 | 290 | 300 |
| GKPFTGAGYT | DINAVLPAKL | ILMAIALICA | AAVFSAIALR | DLRIPAIGLV | LLLLSSLIVG |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AGWPLIVEQI | SVKPNAAQKE | SEYISRSITA | TRQAYGLTSD | VVTYRNYSGD | SPATAQQVAA |
| 370 | 380 | 390 | 400 | 410 | 420 |
| DRATTSNIRL | LDPTIVSPAF | TQFQQGKNFY | YFPDQLSIDR | YLDRNGNLRD | YVVAARELNP |
| 430 | 440 | 450 | 460 | 470 | 480 |
| DRLIDNQRDW | INRHTVYTHG | NGFIASPANT | VRGIANDPNQ | NGGYPEFLVN | VVGANGTVVS |
| 490 | 500 | 510 | 520 | 530 | 540 |
| DGPAPLDQPR | IYFGPVISNT | SADYAIVGRN | GDDREYDYET | NIDTKRYTYT | GSGGVPLGGW |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LARSVFAAKF | AERNFLFSNV | IGSNSKILFN | RDPAQRVEAV | APWLTTDSAV | YPAIVNKRLV |
| 610 | 620 | 630 | 640 | 650 | 660 |
| WIVDGYTTLD | NYPYSELTSL | SSATADSNEV | AFNRLVPDKK | VSYIRNSVKA | TVDAYDGTVT |
| 670 | 680 | 690 | 700 | 710 | 720 |
| LYQQDEKDPV | LKAWMQVFPG | TVKPKSDIAP | ELAEHLRYPE | DLFKVQRMLL | AKYHVNDPVT |
| 730 | 740 | 750 | 760 | 770 | 780 |
| FFSTSDFWDV | PLDPNPTASS | YQPPYYIVAK | NIAKDDNSAS | YQLISAMNRF | KRDYLAAYIS |
| 790 | 800 | 810 | 820 | 830 | 840 |
| ASSDPATYGN | LTVLTIPGQV | NGPKLANNAI | TTDPAVSQDL | GVIGRDNQNR | IRWGNLLTLP |
| 850 | 860 | 870 | 880 | 890 | 900 |
| VAQGGLLYVE | PVYASPGASD | AASSYPRLIR | VAMMYNDKVG | YGPTVRDALT | GLFGPGAGAT |
| 910 | 920 | 930 | 940 | 950 | 960 |
| ATGIAPTEAA | VPPSPAANPP | PPASGPQPPP | VTAAPPVPVG | AVTLSPAKVA | ALQEIQAAIG |
| 970 | 980 | 990 | |||
| AARDAQKKGD | FAAYGSALQR | LDEAITKFND | AG |