AiPD: Autoinhibited Protein Database

Gene name	Enkd1
Protein name	Enkurin domain-containing protein 1
Names
Species	Mus musculus (Mouse)
KEGG Pathway	mmu:102124
EC number
Protein Class

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

54-261 (Predicted disordered autoinhibitory region) PR

54-261 (Predicted disordered autoinhibitory region)

cis-regPred

No accessory elements

Entry ID	Method	Resolution	Chain	Position	Source
AF-Q7TSV9-F1	Predicted				AlphaFoldDB

Variant ID(s)	Position	Change	Diseaes Association	Provenance
rs3389013415	78	L>M	No	EVA
rs3388999663	81	L>M	No	EVA
rs251306690	87	G>S	No	EVA
rs215323862	96	N>D	No	EVA
rs46586179	128	K>N	No	EVA
rs3389008454	136	S>*	No	EVA
rs3388976114	176	P>L	No	EVA
rs223858840	179	R>C	No	EVA
rs262200941	186	A>T	No	EVA
rs3389004886	187	L>R	No	EVA
rs242573214	191	Q>R	No	EVA
rs3389008419	203	S>N	No	EVA
rs239791566	204	R>H	No	EVA
rs214776457	206	A>V	No	EVA
rs3389005037	214	R>G	No	EVA
rs255251594	216	H>Y	No	EVA
rs3389004657	226	V>L	No	EVA
rs248844159	255	L>Q	No	EVA
rs3389008450	263	R>C	No	EVA
rs51595343	265	R>H	No	EVA
rs3388995445	274	P>S	No	EVA
rs3388995416	275	G>R	No	EVA
rs3389005030	276	H>P	No	EVA
rs3389004629	276	H>Y	No	EVA
rs3389004900	298	L>M	No	EVA
rs3388976105	307	A>T	No	EVA

Type	Name	Position	InterPro Accession
domain	Enkurin domain	243 - 343	IPR027012

		Description
EC Number
Subcellular Localization	Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole Cytoplasm, cytoskeleton, cilium basal body Cell projection, cilium Cytoplasm, cytoskeleton, spindle Cytoplasm, cytoskeleton, spindle pole Cytoplasm, cytoskeleton, cilium axoneme	Localized at the centrosome and accumulates at the parental centrioles during centriole duplication in cycling cells (By similarity) In ciliated cells, detected at the basal body of the cilium (By similarity) Localizes to the centrosome during interphase, to the primary cilium at G0, to the spindle poles during mitosis and to the centrosomes and central spindle during telophase and cytokinesis (By similarity)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category	No pathway information available

Name	Definition
9+0 non-motile cilium	A non-motile cilium where the axoneme has a ring of nine outer microtubule doublets but no central microtubules (and is therefore called a 9+0 axoneme).
ciliary base	Area of the cilium (also called flagellum) where the basal body and the axoneme are anchored to the plasma membrane. The ciliary base encompasses the distal part of the basal body, transition fibers and transition zone and is structurally and functionally very distinct from the rest of the cilium. In this area proteins are sorted and filtered before entering the cilium, and many ciliary proteins localize specifically to this area.
cytoplasmic microtubule	Any microtubule in the cytoplasm of a cell.
microtubule cytoskeleton	The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.

Name	Definition
No GO annotations for molecular function

Name	Definition
No GO annotations for biological process

UniProt AC	Gene Name	Protein Name	Species	Evidence Code
No homologous proteins