Q7TQA8

PR
Gene name
Tas2r136 (T2r52, Tas2r36)
Protein name
Taste receptor type 2 member 136
Names
T2R136, Taste receptor type 2 member 36, T2R36, mT2r52
Species
Mus musculus (Mouse)
KEGG Pathway
mmu:353165
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

176-246 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7TQA8

Entry ID Method Resolution Chain Position Source
AF-Q7TQA8-F1 Predicted AlphaFoldDB

No variants for Q7TQA8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7TQA8

No associated diseases with Q7TQA8

No regional properties for Q7TQA8

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q7TQA8

Functions

Description
EC Number
Subcellular Localization
  • Membrane; Multi-pass membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
integral component of membrane The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

3 GO annotations of molecular function

Name Definition
bitter taste receptor activity Combining with soluble bitter compounds to initiate a change in cell activity. These receptors are responsible for the sense of bitter taste.
G protein-coupled receptor activity Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
taste receptor activity Combining with soluble compounds to initiate a change in cell activity. These receptors are responsible for the sense of taste.

1 GO annotations of biological process

Name Definition
detection of chemical stimulus involved in sensory perception of bitter taste The series of events required for a bitter taste stimulus to be received and converted to a molecular signal.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMSFLVSIAS IAMLVKIVLG TFANVFIVLV NFTDCIKKRK FLLADRILTV LAIFRFDLLW
70 80 90 100 110 120
IILMNWSSSV FHVGLYFQVR FCICVVWIVT NHFNTWLANI LSILYLLKID NFSNLIFLGL
130 140 150 160 170 180
KGKIKCPYIV LLPCFVLLFP NLIMVTICET TQANGHQGNL TGKTKLTYFT NLIAMTFTLG
190 200 210 220 230 240
SLVPFTTFMI CFLLLICSLC KHLRTMRLYG KGSQGPSAST HIKVLQVLIS FLLLFSMFIL
250 260 270 280 290 300
LLIISDYNYT KSLEEPIHLI CQVIGTLYPS RHSYILLWGN KRIKQAFVLA MVQVRARFWL
KEKKP