Q7TNY6

PR
Gene name
Acbd3 (Gcp60)
Protein name
Golgi resident protein GCP60
Names
Acyl-CoA-binding domain-containing protein 3, DMT1-associated protein, DAP, Golgi complex-associated protein 1, GOCAP1, Golgi phosphoprotein 1, GOLPH1
Species
Rattus norvegicus (Rat)
KEGG Pathway
rno:289312
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

151-233 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7TNY6

Entry ID Method Resolution Chain Position Source
AF-Q7TNY6-F1 Predicted AlphaFoldDB

No variants for Q7TNY6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7TNY6

No associated diseases with Q7TNY6

2 regional properties for Q7TNY6

Type Name Position InterPro Accession
conserved_site Aminoacyl-tRNA synthetase, class I, conserved site 40 - 50 IPR001412
domain RNA-binding S4 domain 366 - 427 IPR002942

Functions

Description
EC Number
Subcellular Localization
  • Golgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side
  • Mitochondrion
  • Also mitochondrial (via its interaction with PBR)
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Golgi membrane The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

2 GO annotations of molecular function

Name Definition
fatty-acyl-CoA binding Binding to a fatty-acyl-CoA, any derivative of coenzyme A in which the sulfhydryl group is in thiolester linkage with a fatty acyl group.
protein kinase A regulatory subunit binding Binding to one or both of the regulatory subunits of protein kinase A.

1 GO annotations of biological process

Name Definition
steroid biosynthetic process The chemical reactions and pathways resulting in the formation of steroids, compounds with a 1,2,cyclopentanoperhydrophenanthrene nucleus; includes de novo formation and steroid interconversion by modification.

1 homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
Q9H3P7 ACBD3 Golgi resident protein GCP60 Homo sapiens (Human) PR
10 20 30 40 50 60
MAAQLNVEQL EVSLDGLTLS PDSEERPGAE GAPLQTPPSS PPRDGLGSGT AGQQREPGEA
70 80 90 100 110 120
AAEGAAEEAR RMEQHWGFGL EELYGLALRF YKIKDGKAFH PTYEEKLKFV ALHKQVLLGP
130 140 150 160 170 180
YNPDTSPEVG FFDVLGNDRR REWAALGNMS KEDAMVEFVK LLNKCCPLLS AYVASHRIEK
190 200 210 220 230 240
EEEEKRRKAE EERRQREEEE RERLQKEEEK RKREEEDRLR REEEERRRIE EERLRLEQQK
250 260 270 280 290 300
QQIMAALNSQ TAVQFQQYAA QQYPGNYEQQ QILIRQLQEQ HYQQYMQQLY QVQLAQQQAA
310 320 330 340 350 360
LQKQQEVVVA GASLPASTKV NTAGASDPLP VNGQAKTHTE NPEKVLEPEA AEEALENGPK
370 380 390 400 410 420
DSLPVIAAPS MWTRPQIKDF KEKIRQDADS VITVRRGEVV TVRVPTHEEG SYLFWEFATD
430 440 450 460 470 480
SYDIGFGVYF EWTDSPNAAV SVHVSESSDD EEEEEEENVT CEEKAKKNVN KPLLDEIVPV
490 500 510 520
YRRDCHEEVY AGSHQYPGRG VYLLKFDNSY SLWRSKSVYY RVYYTR