Q7T6Y8

PR
Gene name
RNR1 (MIMI_R313)
Protein name
Ribonucleoside-diphosphate reductase large subunit
Names
Ribonucleotide reductase large subunit
Species
Acanthamoeba polyphaga mimivirus (APMV)
KEGG Pathway
vg:9924930
EC number
1.17.4.1: With a disulfide as acceptor
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-86 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

0 structures for Q7T6Y8

Entry ID Method Resolution Chain Position Source

No variants for Q7T6Y8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7T6Y8

No associated diseases with Q7T6Y8

5 regional properties for Q7T6Y8

Type Name Position InterPro Accession
domain Signal transduction response regulator, receiver domain 4 - 121 IPR001789
domain RNA polymerase sigma factor 54 interaction domain 143 - 369 IPR002078
domain DNA binding HTH domain, Fis-type 415 - 453 IPR002197
domain AAA+ ATPase domain 163 - 304 IPR003593
conserved_site Sigma-54 interaction domain, conserved site 353 - 362 IPR025944

Functions

Description
EC Number 1.17.4.1 With a disulfide as acceptor
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

No GO annotations of cellular component

Name Definition
No GO annotations for cellular component

2 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor Catalysis of the reaction: 2'-deoxyribonucleoside diphosphate + thioredoxin disulfide + H2O = ribonucleoside diphosphate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin.

1 GO annotations of biological process

Name Definition
DNA replication The cellular metabolic process in which a cell duplicates one or more molecules of DNA. DNA replication begins when specific sequences, known as origins of replication, are recognized and bound by initiation proteins, and ends when the original DNA molecule has been completely duplicated and the copies topologically separated. The unit of replication usually corresponds to the genome of the cell, an organelle, or a virus. The template for replication can either be an existing DNA molecule or RNA.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNSKNSIILD NLADVSDIID YEQNSIDYQR SIKNIEQLKS TEATEITNKL AINKAKKSSN
70 80 90 100 110 120
ILLEVPKETI YLDHNGSIQV ITSEIIRTYV EKIFEKMEVT HLDIDKMTKN IFPKLKSINT
130 140 150 160 170 180
IKDIDNQIIS TASEMVTDHY DYPKIAVWIL MTNLHDNTSD DFLETAEKLY NNKSESNKNA
190 200 210 220 230 240
PIISENIYNF IKKHIKEINR VIRYDRDYNL TIFGFRTLEK SYLKRINKKI VERPQHLFMR
250 260 270 280 290 300
VAITLHYRKN DLDRIFETYK YLSKGYFTHA TPTLFNAGTT HEQLSSCFLL GIGDSLEEIS
310 320 330 340 350 360
ECWKECALIS KHAGGIGIHM TNIRVEGAYI ASTQGEAGGL RVLTIFNDIS RYANQGGKRP
370 380 390 400 410 420
GSFAIFIEPW HGDIFFFLDL KKNTGAETER ARDLFLGLMI NDIFMERVYK DDVWSLMCPS
430 440 450 460 470 480
QCPNLLNKYG DEFTKEYLKY ESEGIYLKQI RAIDLWFKIM ESQIETGVPY VMFKDAINDK
490 500 510 520 530 540
SNQINIGVVN GSNLCCEIVE VSDKNNFSVC NLSSICLPRF VKIIDEVPTF NYQKLFKISR
550 560 570 580 590 600
ILTRNLNNII DINFYPLDKT RITNLRDRPI GIGVQGLADV FAMFKTPFDS EIARDLNRKI
610 620 630 640 650 660
FETIYYGALT ESNKLAREFG TYQTYQGSPI SQGKFQFDLW NFDKSQLSGM WDWELLRQEI
670 680 690 700 710 720
LNHGVRNSLV TTCMPTASTS QIMGWNECIE PYTENIYSRS TMAGEYFVIN KHLIKDLIEL
730 740 750 760 770 780
GVWNSEMVDL IKYYKGSVAN IPNIPDNIKA IYRTVWEIPQ KSIIEMAADR APFVDQTQSM
790 800 810 820 830 840
NLYIDKPSFA RLNSCLFYAW RKGLKTGMYY LRSKPASSAN QFGIDIDKIK EIESKNGIKK
850 860 870 880
QEDTFDLTDL TNTINQQVSG MVCRFVPAHL RKPGECLSCD G