Q7T0P4

PR
Gene name
poc1a (wdr51a)
Protein name
POC1 centriolar protein homolog A
Names
Pat-interacting protein 2, Pix2, xPix2, WD repeat-containing protein 51A
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:379573
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

388-441 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7T0P4

Entry ID Method Resolution Chain Position Source
AF-Q7T0P4-F1 Predicted AlphaFoldDB

No variants for Q7T0P4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7T0P4

No associated diseases with Q7T0P4

7 regional properties for Q7T0P4

Type Name Position InterPro Accession
repeat WD40 repeat 7 - 88 IPR001680-1
repeat WD40 repeat 91 - 298 IPR001680-2
conserved_site WD40 repeat, conserved site 33 - 47 IPR019775-1
conserved_site WD40 repeat, conserved site 201 - 215 IPR019775-2
repeat G-protein beta WD-40 repeat 117 - 131 IPR020472-1
repeat G-protein beta WD-40 repeat 159 - 173 IPR020472-2
repeat G-protein beta WD-40 repeat 201 - 215 IPR020472-3

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm, cytoskeleton
  • Colocalizes with mitochondria in cortical germ plasm islands
  • The mitochondrial localization may be microtubule-dependent
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
cytoskeleton A cellular structure that forms the internal framework of eukaryotic and prokaryotic cells. The cytoskeleton includes intermediate filaments, microfilaments, microtubules, the microtrabecular lattice, and other structures characterized by a polymeric filamentous nature and long-range order within the cell. The various elements of the cytoskeleton not only serve in the maintenance of cellular shape but also have roles in other cellular functions, including cellular movement, cell division, endocytosis, and movement of organelles.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MAGQSEDPSL ERHFKGHRDT VTAVDFNANT KQLASGSMDS CLMVWNMKTQ MRAYRFVGHK
70 80 90 100 110 120
DAILSVDFSP SGHLIASASR DKTVRLWVPS VKGESTAFKA HTGTVRSVSF SGDGQSLVTA
130 140 150 160 170 180
SDDKTIKVWT VHRQKFLFSL NQHINWVRCA KFSPDGRLIV SASDDKTIKL WDKTSRECIQ
190 200 210 220 230 240
SFCEHGGFVN FVDFHPSGTC IAAAATDNTV KVWDIRMNKL IQHYQVHSGV VNSLSFHPSG
250 260 270 280 290 300
NYLITASNDS TLKVLDLLEG RLLYTLHGHQ GPVTCVKFSR EGDFFASGGS DEQVMVWKTN
310 320 330 340 350 360
FDAGSYPDLL KYRQNDTFPS GGDYTSIVQP ADVHQPARNA HVTQAADLEP HITEMSVKDR
370 380 390 400 410 420
SSPLSYTSRS VDQHHPQAED GNLQTVASTL EHIVGQLDIL TRTVGILEQR LSLTEDKLKE
430 440
CIEQQQATVP PSHSGTKKSS F