Q7SYH5
Gene name |
slc5a8 |
Protein name |
Sodium-coupled monocarboxylate transporter 1 |
Names |
Electrogenic sodium monocarboxylate cotransporter, xSMCTe, Sodium solute transporter Vito, Solute carrier family 5 member 8 |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:403396 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7SYH5
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7SYH5-F1 | Predicted | AlphaFoldDB |
No variants for Q7SYH5
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7SYH5 | |||||
No associated diseases with Q7SYH5
9 regional properties for Q7SYH5
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| repeat | WD40 repeat | 201 - 250 | IPR001680-1 |
| repeat | WD40 repeat | 252 - 424 | IPR001680-2 |
| repeat | WD40 repeat | 426 - 468 | IPR001680-3 |
| repeat | WD40 repeat | 471 - 511 | IPR001680-4 |
| domain | LIS1 homology motif | 6 - 38 | IPR006594 |
| domain | CTLH, C-terminal LisH motif | 40 - 92 | IPR006595 |
| repeat | G-protein beta WD-40 repeat | 228 - 242 | IPR020472-1 |
| repeat | G-protein beta WD-40 repeat | 278 - 292 | IPR020472-2 |
| repeat | G-protein beta WD-40 repeat | 362 - 376 | IPR020472-3 |
1 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| symporter activity | Enables the active transport of a solute across a membrane by a mechanism whereby two or more species are transported together in the same direction in a tightly coupled process not directly linked to a form of energy other than chemiosmotic energy. |
1 GO annotations of biological process
| Name | Definition |
|---|---|
| sodium ion transport | The directed movement of sodium ions (Na+) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MVTPGNIGSF | TVWDYLVFAL | MLLISAVIGI | YYAFAGGGQK | TSKDFLMGGR | SMTAVPVALS |
| 70 | 80 | 90 | 100 | 110 | 120 |
| LTASFMSAVT | VLGTPAEVYR | FGAMFIIFAF | SYTIVVIISS | EVFLPVFYRL | GITSTYEYLE |
| 130 | 140 | 150 | 160 | 170 | 180 |
| LRFNKFVRLL | GTILFIIQTV | LYTGIVIYAP | ALALNQVTGF | DLWGAVVATG | VVCTFYCTMG |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GLKAVVWTDV | FQVGIMVAGF | TSVIIRAVVV | QGGIGPILND | SYYGDRLNFW | DFDPNPLKRH |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TFWTIVVGGT | FTWTGIYGVN | QAQVQRYIAC | KTRFQAKMSL | YVNLIGLWAI | LACAVLSGLA |
| 310 | 320 | 330 | 340 | 350 | 360 |
| MYSIYKDCDP | WTAKFVSAPD | QLMPYLALDI | LRDYPGLPGL | FVSCAYSGTL | STVSSSINAL |
| 370 | 380 | 390 | 400 | 410 | 420 |
| AAVTVEDLIK | PYIRSLSEKK | MSWISKGTSL | LYGAICIGMA | GIASLMGGLL | QAALSIFGMV |
| 430 | 440 | 450 | 460 | 470 | 480 |
| GGPLLGLFSL | GILFPFVNSL | GAVIGLLSGF | AISLWVGIGS | QIYAPSPSSS | LPKPLSLEGC |
| 490 | 500 | 510 | 520 | 530 | 540 |
| NFTSIESNWT | STVMPMMTTL | IPETQVSSRP | ELADSWYSLS | YLYFSTIGTI | VAVLVGVIVS |
| 550 | 560 | 570 | 580 | 590 | 600 |
| LLSGGLKQNV | NREFLLTSED | FSYLNVLFSP | CKEKGQEEKV | EVLNWKARRT | DNDMEQGTDN |
| 610 | 620 | ||||
| PAFNNMEMTS | TEKGEKTNGI | TA |