Q7SY73
Gene name |
abhd6-b |
Protein name |
Monoacylglycerol lipase abhd6-B |
Names |
Abhydrolase domain-containing protein 6-B |
Species |
Xenopus laevis (African clawed frog) |
KEGG Pathway |
xla:380544 |
EC number |
3.1.1.23: Carboxylic ester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7SY73
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7SY73-F1 | Predicted | AlphaFoldDB |
No variants for Q7SY73
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7SY73 | |||||
No associated diseases with Q7SY73
1 regional properties for Q7SY73
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | Alpha/beta hydrolase fold-1 | 72 - 313 | IPR000073 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.1.23 | Carboxylic ester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| integral component of membrane | The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane. |
| late endosome membrane | The lipid bilayer surrounding a late endosome. |
| lysosomal membrane | The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm. |
| mitochondrial membrane | Either of the lipid bilayers that surround the mitochondrion and form the mitochondrial envelope. |
1 GO annotations of molecular function
| Name | Definition |
|---|---|
| acylglycerol lipase activity | Catalysis of the reaction: H2O + acylglycerol = a fatty acid + glycerol. |
3 GO annotations of biological process
| Name | Definition |
|---|---|
| acylglycerol catabolic process | The chemical reactions and pathways resulting in the breakdown of acylglycerol, any mono-, di- or triester of glycerol with (one or more) fatty acids. |
| lysobisphosphatidic acid metabolic process | The chemical reactions and pathways involving a lysobisphosphatidic acid. A lysobisphosphatidic acid is a lysophosphatidic acid having the unusual property of a phosphodiester moiety linked to positions sn-1 and sn1' of glycerol; and two additional fatty acids esterified to the glycerol head group. |
| monoacylglycerol catabolic process | The chemical reactions and pathways resulting in the breakdown of monoacylglycerol, any ester of glycerol in which any one of its hydroxyl groups has been acylated with a fatty acid, the other being non-esterified. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MDIDVLNMFL | VAGGTLLVPL | LAFMTSFLLW | PAALIRIYYW | YWRRALGMQV | KYSSYGNYKF |
| 70 | 80 | 90 | 100 | 110 | 120 |
| CYTARGKPGN | KPSVLMLHGF | SAHKDMWLGM | VKFLPKNLHL | VCVDMPGHEG | TSRSALDYYS |
| 130 | 140 | 150 | 160 | 170 | 180 |
| ICGQVKRIHQ | FVESIGLNKK | PFHLVGTSMG | GNVAGVYAAQ | HPTHISSLTL | ICPAGLMYPI |
| 190 | 200 | 210 | 220 | 230 | 240 |
| ESKFLKQLKV | LEKSGDNQRI | PLIPSTAGEM | EDMLRLCSFV | RFKIPQQVLQ | GLIDERIPHN |
| 250 | 260 | 270 | 280 | 290 | 300 |
| EFYRKLFLAL | VDEKSRHSLH | ENMNKIMAPT | QIIWGKQDQV | LDVSGAEVLA | GSLRGCQVEI |
| 310 | 320 | 330 | |||
| LENCGHSVVM | ERPRKSAKLM | TDFLSSLQST | DNHKKHD |