Q7SY65

PR
Gene name
krt18-b
Protein name
Keratin, type I cytoskeletal 18-B
Names
Cytokeratin-18-B, CK-18-B, Keratin-18-B, K18-B
Species
Xenopus laevis (African clawed frog)
KEGG Pathway
xla:380504
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-111 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7SY65

Entry ID Method Resolution Chain Position Source
AF-Q7SY65-F1 Predicted AlphaFoldDB

No variants for Q7SY65

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7SY65

No associated diseases with Q7SY65

2 regional properties for Q7SY65

Type Name Position InterPro Accession
conserved_site Intermediate filament protein, conserved site 379 - 387 IPR018039
domain Intermediate filament, rod domain 82 - 393 IPR039008

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
intermediate filament A cytoskeletal structure that forms a distinct elongated structure, characteristically 10 nm in diameter, that occurs in the cytoplasm of eukaryotic cells. Intermediate filaments form a fibrous system, composed of chemically heterogeneous subunits and involved in mechanically integrating the various components of the cytoplasmic space. Intermediate filaments may be divided into five chemically distinct classes: Type I, acidic keratins; Type II, basic keratins; Type III, including desmin, vimentin and others; Type IV, neurofilaments and related filaments; and Type V, lamins.

1 GO annotations of molecular function

Name Definition
structural molecule activity The action of a molecule that contributes to the structural integrity of a complex or its assembly within or outside a cell.

No GO annotations of biological process

Name Definition
No GO annotations for biological process

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSYSRSMYSS SSVVGGSPYR SLSSAPRFAP GSSAASVHAG PGGSGARISV SRVSSVGSGF
70 80 90 100 110 120
GGGFSGGFSG VSNVSLMGGA QNEKETMQDL NDRLASYLER VRSLETANKE LEVQIRQHTE
130 140 150 160 170 180
KKGPAKDWSP YYKAIEDLKK QVFDSTVDNS QLVLQIDNAR LAADDFRVKY EAELAIRMSV
190 200 210 220 230 240
ETDIGGLRKL IDDTNISRLN LENEIESLKE ELIFLKKNHQ DDVNELQAQI ARSAVTVEVD
250 260 270 280 290 300
APKSQDLGKI MAELRAQYDG LAQKNREDVE KWYQSKVEEH TMQVNIDTQE LQTSKNSVTE
310 320 330 340 350 360
LRRTMQSLEI ELESLRNQKA SLEGTLHDTE ARYAMELEML GGTAMARESE LVQVRSDCQR
370 380 390 400 410 420
QQQEYQALLN TKMKLEAEIH TYRRLLEGDS FDLQDAVPTV TTQTVKKVIT TTQRIVDGKV
430
VAESNDTEVL KA