Q7SIG4
Gene name |
|
Protein name |
Diisopropyl-fluorophosphatase |
Names |
DFPase |
Species |
Loligo vulgaris (Common European squid) |
KEGG Pathway |
|
EC number |
3.1.8.2: Phosphoric triester hydrolases |
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
32 structures for Q7SIG4
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| 1E1A | X-ray | 180 A | A | 1-314 | PDB |
| 1PJX | X-ray | 085 A | A | 1-314 | PDB |
| 2GVU | X-ray | 200 A | A | 1-314 | PDB |
| 2GVV | X-ray | 173 A | A | 1-314 | PDB |
| 2GVW | X-ray | 186 A | A | 1-314 | PDB |
| 2GVX | X-ray | 200 A | A | 1-314 | PDB |
| 2IAO | X-ray | 200 A | A | 3-314 | PDB |
| 2IAP | X-ray | 190 A | A | 3-314 | PDB |
| 2IAQ | X-ray | 210 A | A | 3-314 | PDB |
| 2IAR | X-ray | 190 A | A | 3-314 | PDB |
| 2IAS | X-ray | 200 A | A | 3-314 | PDB |
| 2IAT | X-ray | 190 A | A | 3-314 | PDB |
| 2IAU | X-ray | 200 A | A | 3-314 | PDB |
| 2IAV | X-ray | 107 A | A | 3-314 | PDB |
| 2IAW | X-ray | 174 A | A | 3-314 | PDB |
| 2IAX | X-ray | 110 A | A | 3-314 | PDB |
| 3BYC | X-ray | 220 A | A | 1-314 | PDB |
| 3HLH | X-ray | 180 A | A/B/C/D | 1-314 | PDB |
| 3HLI | X-ray | 140 A | A/B/C/D | 1-314 | PDB |
| 3I1C | X-ray | 220 A | A | 1-314 | PDB |
| 3KGG | X-ray | 210 A | A | 1-314 | PDB |
| 3LI3 | X-ray | 166 A | A | 1-314 | PDB |
| 3LI4 | X-ray | 135 A | A | 1-314 | PDB |
| 3LI5 | X-ray | 136 A | A | 1-314 | PDB |
| 3O4P | X-ray | 085 A | A | 1-314 | PDB |
| 3U0S | X-ray | 260 A | A/B | 1-314 | PDB |
| 4O5S | X-ray | 180 A | A/B | 1-314 | PDB |
| 4O5T | X-ray | 290 A | A/B | 1-314 | PDB |
| 7ZP5 | X-ray | 154 A | A/B | 1-314 | PDB |
| 7ZP6 | X-ray | 190 A | A | 1-314 | PDB |
| 7ZP7 | X-ray | 170 A | A/B | 1-310 | PDB |
| AF-Q7SIG4-F1 | Predicted | AlphaFoldDB |
No variants for Q7SIG4
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7SIG4 | |||||
No associated diseases with Q7SIG4
3 regional properties for Q7SIG4
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| conserved_site | 14-3-3 protein, conserved site | 46 - 56 | IPR023409-1 |
| conserved_site | 14-3-3 protein, conserved site | 218 - 237 | IPR023409-2 |
| domain | 14-3-3 domain | 6 - 249 | IPR023410 |
Functions
| Description | ||
|---|---|---|
| EC Number | 3.1.8.2 | Phosphoric triester hydrolases |
| Subcellular Localization |
|
|
| PANTHER Family | ||
| PANTHER Subfamily | ||
| PANTHER Protein Class | ||
| PANTHER Pathway Category | No pathway information available | |
No GO annotations of cellular component
| Name | Definition |
|---|---|
| No GO annotations for cellular component |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| calcium ion binding | Binding to a calcium ion (Ca2+). |
| diisopropyl-fluorophosphatase activity | Catalysis of the reaction: diisopropyl fluorophosphate + H(2)O = diisopropyl phosphate + 2 H(+) + hydrogen fluoride. |
No GO annotations of biological process
| Name | Definition |
|---|---|
| No GO annotations for biological process |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MEIPVIEPLF | TKVTEDIPGA | EGPVFDKNGD | FYIVAPEVEV | NGKPAGEILR | IDLKTGKKTV |
| 70 | 80 | 90 | 100 | 110 | 120 |
| ICKPEVNGYG | GIPAGCQCDR | DANQLFVADM | RLGLLVVQTD | GTFEEIAKKD | SEGRRMQGCN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| DCAFDYEGNL | WITAPAGEVA | PADYTRSMQE | KFGSIYCFTT | DGQMIQVDTA | FQFPNGIAVR |
| 190 | 200 | 210 | 220 | 230 | 240 |
| HMNDGRPYQL | IVAETPTKKL | WSYDIKGPAK | IENKKVWGHI | PGTHEGGADG | MDFDEDNNLL |
| 250 | 260 | 270 | 280 | 290 | 300 |
| VANWGSSHIE | VFGPDGGQPK | MRIRCPFEKP | SNLHFKPQTK | TIFVTEHENN | AVWKFEWQRN |
| 310 | |||||
| GKKQYCETLK | FGIF |