Q7SBR1

PR
Gene name
drh-15 (mrh4, NCU06246)
Protein name
ATP-dependent RNA helicase mrh4, mitochondrial
Names
DEAD box RNA helicase 15
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
KEGG Pathway
ncr:NCU06246
EC number
3.6.4.13: Acting on ATP; involved in cellular and subcellular movement
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

10-144 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7SBR1

Entry ID Method Resolution Chain Position Source
AF-Q7SBR1-F1 Predicted AlphaFoldDB

No variants for Q7SBR1

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7SBR1

No associated diseases with Q7SBR1

3 regional properties for Q7SBR1

Type Name Position InterPro Accession
domain Helicase, C-terminal 453 - 625 IPR001650
domain DEAD/DEAH box helicase domain 173 - 392 IPR011545
domain Helicase superfamily 1/2, ATP-binding domain 168 - 417 IPR014001

Functions

Description
EC Number 3.6.4.13 Acting on ATP; involved in cellular and subcellular movement
Subcellular Localization
  • Mitochondrion
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrion A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
nucleus A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
ATP hydrolysis activity Catalysis of the reaction: ATP + H2O = ADP + H+ phosphate. ATP hydrolysis is used in some reactions as an energy source, for example to catalyze a reaction or drive transport against a concentration gradient.
RNA binding Binding to an RNA molecule or a portion thereof.
RNA helicase activity Unwinding of an RNA helix, driven by ATP hydrolysis.

1 GO annotations of biological process

Name Definition
rRNA processing Any process involved in the conversion of a primary ribosomal RNA (rRNA) transcript into one or more mature rRNA molecules.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MWKTARDSVC LICRSAATTT TSTSARASLE PWAGQRTFST RREQRPSRMV LSDRVARPPP
70 80 90 100 110 120
VRGPGEGNKK PRNKPDGPWA GMNRRVANID PRKAPKPKPV EEDSRRDKRD KNTKGQKALK
130 140 150 160 170 180
MQRALATISY GQRTSIKERM QEIQAFDQFD LLPVVKEAIA QEALKGMTEI KPTPVQRLAI
190 200 210 220 230 240
PALLGQPMGR KPRRPKSDNG REEFLLAAET GSGKTLAYLV PAVNAIKKGD ADDELVASYN
250 260 270 280 290 300
ERLAAEKERR GGAPVSEWIE KFEPHPNTAR PRVVVLVPTA ELVDQVTSVA KKLAHYTKFK
310 320 330 340 350 360
VRPLSASISP LRNQRNLYSP IGVDMIVSTP HLLATIAKSD PNVLSRVSHL VIDEADSLLD
370 380 390 400 410 420
RSFSGDTTSI VDRAMPSLKQ LILCSATIPR RLDTYMEEQF PYINRITTPN LHAIPRRVQL
430 440 450 460 470 480
GVIDVSKDPY RNNKMLACAD AIWSIGKEAA KHEGPKSEID VKRIMVFVNE RETTQQVADY
490 500 510 520 530 540
LVSKGIDAIA LHRDTEEHRK SEMLASFTSN EPMKISRPAD DDVAAAAAEG GKAGGAVSSS
550 560 570 580 590 600
PTRRHLPNTK VIVATDLASR GIDTLAVRYV VLYDVPHTTI DFIHRLGRAG RMNRRGRGIV
610 620
LVGKDDRRDV VAEVKESMFM GQALV