Q7SB54

PR
Gene name
vsp-6 (snx41, NCU06259)
Protein name
Sorting nexin-41
Names
Vacuolar sorting protein 6
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
KEGG Pathway
ncr:NCU06259
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

17-104 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7SB54

Entry ID Method Resolution Chain Position Source
AF-Q7SB54-F1 Predicted AlphaFoldDB

No variants for Q7SB54

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7SB54

No associated diseases with Q7SB54

3 regional properties for Q7SB54

Type Name Position InterPro Accession
domain Phox homology 106 - 224 IPR001683
domain Sorting nexin/Vps5-like, C-terminal 296 - 447 IPR015404
domain Snx41 /Atg20, PX domain 111 - 221 IPR044106

Functions

Description
EC Number
Subcellular Localization
  • Endosome membrane ; Peripheral membrane protein
  • Endomembrane system ; Peripheral membrane protein
  • Endosome and other perivacuolar punctate structures
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytosol The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
endosome membrane The lipid bilayer surrounding an endosome.

1 GO annotations of molecular function

Name Definition
phosphatidylinositol binding Binding to an inositol-containing glycerophospholipid, i.e. phosphatidylinositol (PtdIns) and its phosphorylated derivatives.

3 GO annotations of biological process

Name Definition
autophagy The cellular catabolic process in which cells digest parts of their own cytoplasm; allows for both recycling of macromolecular constituents under conditions of cellular stress and remodeling the intracellular structure for cell differentiation.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
retrograde transport, endosome to Golgi The directed movement of membrane-bounded vesicles from endosomes back to the trans-Golgi network where they are recycled for further rounds of transport.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MWNDEDNNPY GSFERRDSFA SSTNPASPTA RDYSIDARFP TPQDVRYDAP LTPSDAGDDE
70 80 90 100 110 120
VPGPTYPREA SDAATDDETD DQAHGELVPR RKPGGYDSRI EQMLYENPEL PILITEAGKS
130 140 150 160 170 180
QESGGRFIVY TIKTGDLTVR RRYSEFASLR DALTRLHPTL VIPPIPEKHT MADYAANPTN
190 200 210 220 230 240
AKQDQQIIDL RKRMLAVFLN RCRRMEQVRT DGVWWRFLDP NSSWTEVLHS HPVSSIPKQI
250 260 270 280 290 300
MKAPPLDPAN PTAGHSFLPV PSSSAKLKTL PTQALDSAAA ASLARFPPDA NSLSEQDLDA
310 320 330 340 350 360
YFIAFETSIK DLESLLTGPM EKVNRRTLNH LSSLASDLSE LGARYNAFAL SETAPTVSAA
370 380 390 400 410 420
IERVGQAADS SYIATEELST SLSASFAEPM RESAQFAGVV RNVLRYRILK RVQQEMTTDE
430 440 450 460 470 480
LNKKKALLES LERSEAEARR IDQYLSSSQQ IQPPRREPPA QHRRDGSGED TASIDSDFPP
490 500 510 520 530 540
THSDFSQAPS AKIGAPERTG GSPSHKKAAS TSITNKIFGP IRHAVQGVVD VDPERTRRDT
550 560 570 580 590 600
IGKTRESIVQ LEQAQIASAK DVKDASASVL KDLKRFQREK EDDLKRYMLA YAKSQIEWAK
610
KNQETWEEAK AEVNKINES