Q7S7C0

PR
Gene name
cym-1 (B13M13.120, NCU01272)
Protein name
Mitochondrial presequence protease
Names
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
KEGG Pathway
ncr:NCU01272
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

253-322 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7S7C0

Entry ID Method Resolution Chain Position Source
AF-Q7S7C0-F1 Predicted AlphaFoldDB

No variants for Q7S7C0

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7S7C0

No associated diseases with Q7S7C0

4 regional properties for Q7S7C0

Type Name Position InterPro Accession
domain Peptidase M16, C-terminal 232 - 419 IPR007863-1
domain Peptidase M16, C-terminal 834 - 923 IPR007863-2
domain Peptidase M16, N-terminal 72 - 160 IPR011765
domain Peptidase M16C associated 489 - 747 IPR013578

Functions

Description
EC Number
Subcellular Localization
  • Mitochondrion intermembrane space
  • Mitochondrion matrix
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
mitochondrial intermembrane space The region between the inner and outer lipid bilayers of the mitochondrial envelope.
mitochondrial matrix The gel-like material, with considerable fine structure, that lies in the matrix space, or lumen, of a mitochondrion. It contains the enzymes of the tricarboxylic acid cycle and, in some organisms, the enzymes concerned with fatty acid oxidation.

2 GO annotations of molecular function

Name Definition
metal ion binding Binding to a metal ion.
metalloendopeptidase activity Catalysis of the hydrolysis of internal, alpha-peptide bonds in a polypeptide chain by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.

2 GO annotations of biological process

Name Definition
protein processing Any protein maturation process achieved by the cleavage of a peptide bond or bonds within a protein. Protein maturation is the process leading to the attainment of the full functional capacity of a protein.
proteolysis involved in protein catabolic process The hydrolysis of a peptide bond or bonds within a protein as part of the chemical reactions and pathways resulting in the breakdown of a protein by individual cells.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MLRNATKGAA RRAVTELSQY PKPGEKLHGF TLLRSKHVPE LELTALHLQH DKTGAEHLHI
70 80 90 100 110 120
ARDDSNNVFS IGFKTNPPDD TGVPHILEHT TLCGSQKYPI RDPFFKMLPR TLSNFMNAFT
130 140 150 160 170 180
ASDHTFYPFA TTNAQDFKNL MSVYLDATLH PLLKETDFTQ EGWRIGPENP QALVAAEGNA
190 200 210 220 230 240
KPEDRKLVFK GVVYNEMKGQ MSDAAYLFWI RFQDHIFPDI HNSGGDPQKI TDLTYQQLKK
250 260 270 280 290 300
FHADHYHPSN AKVFTYGDMP LADHLKEIGA QLDVFEKIRA DVAHHSPIDL SSGPREVKLY
310 320 330 340 350 360
GPIDPLVDAN KQFKTSVSWV LGETNNVVES FSLALISALL MDGYGSPLYK GLIESGLGTD
370 380 390 400 410 420
WSPNTGYDSS GKLGIFSIGL SGVQEEDVPK VKAKVQEILR SMRDKGFERS KIDGYLHQLE
430 440 450 460 470 480
LGLKHKTANF GMSLLHRLKP KWFVGVDPFD SLAWNDTIAA FETELAKGGY LEGLIDKYLI
490 500 510 520 530 540
NDNTLSFTMA PSPTFSQELA QEEETRLSTK ISEVVKAAGS EEEARAALEA RELKLLAEQS
550 560 570 580 590 600
KTNTEDLGCL PSVHVKDIPR QKDSVILRHD NTARVKTQWH EAPTNGLTYF RAINQLENLP
610 620 630 640 650 660
DELRSLIPLF TDSIMRLGTK DMTMEQLEDL IKLKTGGVSV GYHSASHPTD FTRATEGLMF
670 680 690 700 710 720
SGMALDRHVP TMFDLLRKLV VETDFDSPQA AQQIRQLLQA SADGVVNDIA SSGHAYARRA
730 740 750 760 770 780
AESGLTWDSF LKEQVSGLSQ VKLVTSLASR PESDPLEDVI AKLKQIQQFA LAGNLRTAIT
790 800 810 820 830 840
CDSGSVSDNA KALLNFVNSL PSEAVTFPSR GPPNFTRDIK TFYPLPYQVY YGALALPTAS
850 860 870 880 890 900
YTASVNAPLQ ILSQLLTHKH LHHEIREKGG AYGGGSYARP LDGIFGFYSY RDPNPVNTLK
910 920 930 940 950 960
IMRNAGQWAV DKEWTDRDLE DAKISVFQGV DAPKAVNEEG MAQFLYGITD EMKQKRREEL
970 980 990 1000 1010
LDVTKDQVRE VAQEYVVKAL NNGSERVVFL GEKRDWVDKS WAVKEMDING ST