Q7S4C1
Gene name |
sfh-5 (NCU02200) |
Protein name |
Phosphatidylinositol transfer protein sfh-5 |
Names |
PITP sfh-5 |
Species |
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) |
KEGG Pathway |
ncr:NCU02200 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7S4C1
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7S4C1-F1 | Predicted | AlphaFoldDB |
No variants for Q7S4C1
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7S4C1 | |||||
No associated diseases with Q7S4C1
1 regional properties for Q7S4C1
| Type | Name | Position | InterPro Accession |
|---|---|---|---|
| domain | CRAL-TRIO lipid binding domain | 187 - 354 | IPR001251 |
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| cortical endoplasmic reticulum | A cortical network of highly dynamic tubules that are juxtaposed to the plasma membrane and undergo ring closure and tubule-branching movements. |
| cytosol | The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
| endoplasmic reticulum membrane | The lipid bilayer surrounding the endoplasmic reticulum. |
| plasma membrane | The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| metal ion binding | Binding to a metal ion. |
| phosphatidylinositol transfer activity | Removes phosphatidylinositol from a membrane or a monolayer lipid particle, transports it through the aqueous phase while protected in a hydrophobic pocket, and brings it to an acceptor membrane or lipid particle. |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| Golgi to plasma membrane protein transport | The directed movement of proteins from the Golgi to the plasma membrane in transport vesicles that move from the trans-Golgi network to the plasma membrane. |
| regulation of exocytosis | Any process that modulates the frequency, rate or extent of exocytosis. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MSTQPSDSAE | PGAAPAAVST | YAGVENTPTV | PGSEPDAAKH | AEEEPKVVNP | TEPQPTAPVD |
| 70 | 80 | 90 | 100 | 110 | 120 |
| NEPKPAAAPA | QEADSPADIK | DSVSTTAGEL | SPLAQLWKAA | EGHAHFEIWG | VPLSDPERHI |
| 130 | 140 | 150 | 160 | 170 | 180 |
| PTQIIFQKFL | NANEGQVEKA | KDQLLKTLDW | RQKTQPQQLL | RKMFSKAKFD | GLGYVTTYTA |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GDEPAVDEPE | QKEVFTWNLY | GSVKSLDETF | GNLQEFVEWR | VALMELGLME | INIGGAIKPI |
| 250 | 260 | 270 | 280 | 290 | 300 |
| TADYDPYKMT | QVHDYKGISF | LRQTDVAKAA | SKECIKVLGD | NYPELLKEKF | FLNIPAIMGF |
| 310 | 320 | 330 | 340 | 350 | 360 |
| FYGLMKMFVS | KKTLNKFHPM | SSGTNLAKEF | VNTKVDGLGD | KLPAEYGGKG | ADLKTLGKAP |
| IVT |