Q7S083

PR
Gene name
atg12 (NCU10049)
Protein name
Ubiquitin-like protein atg12
Names
Autophagy-related protein 12
Species
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
KEGG Pathway
ncr:NCU10049
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-87 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7S083

Entry ID Method Resolution Chain Position Source
AF-Q7S083-F1 Predicted AlphaFoldDB

No variants for Q7S083

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7S083

No associated diseases with Q7S083

No regional properties for Q7S083

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q7S083

Functions

Description
EC Number
Subcellular Localization
  • Preautophagosomal structure membrane ; Peripheral membrane protein
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
Atg12-Atg5-Atg16 complex A protein complex required for the expansion of the autophagosomal membrane. In budding yeast, this complex consists of Atg12p, Atg5p and Atg16p.
phagophore assembly site membrane A cellular membrane associated with the phagophore assembly site.

No GO annotations of molecular function

Name Definition
No GO annotations for molecular function

5 GO annotations of biological process

Name Definition
autophagosome assembly The formation of a double membrane-bounded structure, the autophagosome, that occurs when a specialized membrane sac, called the isolation membrane, starts to enclose a portion of the cytoplasm.
autophagy of mitochondrion The autophagic process in which mitochondria are delivered to a type of vacuole and degraded in response to changing cellular conditions.
autophagy of nucleus A form of autophagy, by which damaged or non-essential parts of the nucleus, or even an entire nucleus is degraded.
C-terminal protein lipidation The covalent attachment of a lipid group to the carboxy-terminus of a protein.
protein transport The directed movement of proteins into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MASSQPLHGT ASPSLVHDDN NPNSSTASPV LEGRDSPNLP LTMTASTVLM TLPRDATAAL
70 80 90 100 110 120
AEAGTFDQEK VVIRFKPVGS APALRREQVK VLSTHSFETV VAYLRKTLKV QETDSVFLYV
130 140 150
NSVFAPALDE VVGNLWRCFK DSTNQLNVSY SMTPSFG