Q7RUX3
Gene name |
slt-11 (B24P7.250, NCU03007) |
Protein name |
Pre-mRNA-splicing factor slt-11 |
Names |
|
Species |
Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987) |
KEGG Pathway |
ncr:NCU03007 |
EC number |
|
Protein Class |
|
Descriptions
The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.
Autoinhibitory domains (AIDs)
Target domain |
|
Relief mechanism |
|
Assay |
cis-regPred |
Accessory elements
No accessory elements
Autoinhibited structure
Activated structure
1 structures for Q7RUX3
| Entry ID | Method | Resolution | Chain | Position | Source |
|---|---|---|---|---|---|
| AF-Q7RUX3-F1 | Predicted | AlphaFoldDB |
No variants for Q7RUX3
| Variant ID(s) | Position | Change | Description | Diseaes Association | Provenance |
|---|---|---|---|---|---|
| No variants for Q7RUX3 | |||||
No associated diseases with Q7RUX3
4 GO annotations of cellular component
| Name | Definition |
|---|---|
| post-mRNA release spliceosomal complex | A spliceosomal complex that is formed following the release of the spliced product from the post-spliceosomal complex and contains the excised intron and three snRNPs, including U5. |
| Prp19 complex | A protein complex consisting of Prp19 and associated proteins that is involved in the transition from the precatalytic spliceosome to the activated form that catalyzes step 1 of splicing, and which remains associated with the spliceosome through the second catalytic step. It is widely conserved, found in both yeast and mammals, though the exact composition varies. In S. cerevisiae, it contains Prp19p, Ntc20p, Snt309p, Isy1p, Syf2p, Cwc2p, Prp46p, Clf1p, Cef1p, and Syf1p. |
| U2-type catalytic step 1 spliceosome | A spliceosomal complex that is formed by the displacement of the U1 and U4 snRNPs from the precatalytic spliceosome; the U2, U5 and U6 snRNPs remain associated with the mRNA. This complex, sometimes called the activated spliceosome, is the catalytically active form of the spliceosome, and includes many proteins in addition to those found in the U2, and U5 and U6 snRNPs. |
| U2-type catalytic step 2 spliceosome | A spliceosomal complex that contains the U2, U5 and U6 snRNPs bound to a splicing intermediate in which the first catalytic cleavage of the 5' splice site has occurred. The precise subunit composition differs significantly from that of the catalytic step 1, or activated, spliceosome, and includes many proteins in addition to those found in the U2, U5 and U6 snRNPs. |
2 GO annotations of molecular function
| Name | Definition |
|---|---|
| pre-mRNA binding | Binding to a pre-messenger RNA (pre-mRNA), an intermediate molecule between DNA and protein that may contain introns and, at least in part, encodes one or more proteins. Introns are removed from pre-mRNA to form a mRNA molecule. |
| U6 snRNA binding | Binding to a U6 small nuclear RNA (U6 snRNA). |
2 GO annotations of biological process
| Name | Definition |
|---|---|
| mRNA processing | Any process involved in the conversion of a primary mRNA transcript into one or more mature mRNA(s) prior to translation into polypeptide. |
| RNA splicing | The process of removing sections of the primary RNA transcript to remove sequences not present in the mature form of the RNA and joining the remaining sections to form the mature form of the RNA. |
No homologous proteins in AiPD
| UniProt AC | Gene Name | Protein Name | Species | Evidence Code |
|---|---|---|---|---|
| No homologous proteins | ||||
| 10 | 20 | 30 | 40 | 50 | 60 |
| MPPQIKHDLN | RSGWEATDFP | SVCENCLPEN | PYVKMLKEDY | GAECKLCTRP | FTVFSWAADR |
| 70 | 80 | 90 | 100 | 110 | 120 |
| AHARKKRTNI | CLTCARLKNA | CQCCILDLQF | GLPIIIRDKA | LELVAPGPQS | EINREYFAQN |
| 130 | 140 | 150 | 160 | 170 | 180 |
| NERAIEEGRA | GVEEYEKADE | KARELLRRLA | QSKPYFRKGR | EVDEEGNPVN | GSSSGAGRAT |
| 190 | 200 | 210 | 220 | 230 | 240 |
| GGNPAVGAGV | GGVGPIRTRD | SRAAAAAGAR | PGGGRRPNAA | PAPPPGPKDW | LPPADKSIMS |
| 250 | 260 | 270 | 280 | 290 | 300 |
| LFVTGIEDDL | PEFKIRDFFK | AFGKIKSLVV | SHMSHAAFVN | YETREAAEKA | SAECKGRAVI |
| 310 | 320 | 330 | 340 | 350 | 360 |
| AGCPLRVRWS | VPKALGTMNK | EQRSEMLRDG | RSAFGSGQKT | GGQKAIGGQN | AQGGASGAQK |
| 370 | 380 | ||||
| DDASNLTIAA | PPGAADVQYA | SLSGN |