Q7RAV5

PR
Gene name
CDPK3
Protein name
Calcium-dependent protein kinase 3
Names
Species
Plasmodium yoelii yoelii
KEGG Pathway
EC number
2.7.11.1: Protein-serine/threonine kinases
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-131 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

271-275 (Activation loop from InterPro)

Target domain

112-367 (Protein kinase domain)

Relief mechanism

Assay

252-260 (Activation loop from InterPro)

Target domain

112-367 (Protein kinase domain)

Relief mechanism

Assay

References

Autoinhibited structure

Activated structure

1 structures for Q7RAV5

Entry ID Method Resolution Chain Position Source
AF-Q7RAV5-F1 Predicted AlphaFoldDB

No variants for Q7RAV5

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7RAV5

No associated diseases with Q7RAV5

1 regional properties for Q7RAV5

Type Name Position InterPro Accession
conserved_site Phosphatidylethanolamine-binding, conserved site 70 - 92 IPR001858

Functions

Description
EC Number 2.7.11.1 Protein-serine/threonine kinases
Subcellular Localization
  • Cytoplasm
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

4 GO annotations of molecular function

Name Definition
ATP binding Binding to ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
calcium ion binding Binding to a calcium ion (Ca2+).
protein serine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate.
protein serine/threonine kinase activity Catalysis of the reactions: ATP + protein serine = ADP + protein serine phosphate, and ATP + protein threonine = ADP + protein threonine phosphate.

2 GO annotations of biological process

Name Definition
cell differentiation The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
protein phosphorylation The process of introducing a phosphate group on to a protein.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNQLCVERSP NISTATAYIK GKPKKSIERI KKKKDSNKSI KSQHKFEGSK ISNKNNELKD
70 80 90 100 110 120
VKSKDPKNYE SYLNKNTKHK DILLKSKRSD NFKFSRRGFI LSFTGNLEDF YNLSEEPLGK
130 140 150 160 170 180
GTYGCVYKAT DKLLKIQRAV KVVSKKKLKN IPRFRQEIDI MKNLDHPNVI KLLETFEDEE
190 200 210 220 230 240
QIYLIMDLCT GGELFDKIIK KGSFVEMYAS FIMKQIFSVL NYLHIRNICH RDIKPENFLF
250 260 270 280 290 300
YDKSTESLIK IIDFGLAAYF NDIDYEMKTK AGTPYYVAPQ VLTGCYDYKC DLWSAGVLFY
310 320 330 340 350 360
IILCGYPPFY GESDHEILSM VKKGKYNFKG KEWNNISDEA KDLIKRCLTI DSGKRINASE
370 380 390 400 410 420
ALKHPWFKKK KGSFNLDVKM DIHVLENFKN YALLLKLQKL AMTIIAQQSN DYDLQQLKAV
430 440 450 460 470 480
FLYLDEDGKG NITKNQLKKG LENSGLKLPQ NFDVLLDQID SDGSGRIDYT EFLAAALDRK
490 500 510 520 530
HLSKKLIYCA FRVFDVDNDG EITTAELAHV TFFVILFLHH VNDFPRLENC TKYIDLNA