Q7PXY4

PR
Gene name
AGAP001654
Protein name
Histone deacetylase complex subunit SAP30 homolog
Names
Species
Anopheles gambiae (African malaria mosquito)
KEGG Pathway
aga:AgaP_AGAP001654
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

1-128 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7PXY4

Entry ID Method Resolution Chain Position Source
AF-Q7PXY4-F1 Predicted AlphaFoldDB

No variants for Q7PXY4

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7PXY4

No associated diseases with Q7PXY4

2 regional properties for Q7PXY4

Type Name Position InterPro Accession
domain Histone deacetylase complex subunit SAP30 zinc-finger 18 - 88 IPR025717
domain Histone deacetylase complex subunit SAP30, Sin3 binding domain 105 - 157 IPR025718

Functions

Description
EC Number
Subcellular Localization
  • Nucleus
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
histone deacetylase complex A protein complex that possesses histone deacetylase activity.

3 GO annotations of molecular function

Name Definition
DNA binding Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
metal ion binding Binding to a metal ion.
transcription coregulator activity A transcription regulator activity that modulates the transcription of specific gene sets via binding to a DNA-bound DNA-binding transcription factor, either on its own or as part of a complex. Coregulators often act by altering chromatin structure and modifications. For example, one class of transcription coregulators modifies chromatin structure through covalent modification of histones. A second class remodels the conformation of chromatin in an ATP-dependent fashion. A third class modulates interactions of DNA-bound DNA-binding transcription factors with other transcription coregulators.

1 GO annotations of biological process

Name Definition
regulation of DNA-templated transcription Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MMNNNGFSTG EEDSRGPADQ ICCLLDDGER CRKQAGNASY SKRIQKTVTQ RRLKLSIDSH
70 80 90 100 110 120
ARHIYICDFH KARIQCARTK RRRRDSEDDS NETDTDLPEV DLYQLQVNTL RRYKRFYKVS
130 140 150 160 170
TRPSSNKAQL SETIMKHFKT IPIKEKEILT YFIYMVKSNS NKLDQKNNAS AEAT