Q7PWQ6

PR
Gene name
AGAP008883
Protein name
Anamorsin homolog
Names
Fe-S cluster assembly protein DRE2 homolog
Species
Anopheles gambiae (African malaria mosquito)
KEGG Pathway
aga:AgaP_AGAP008883
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

98-242 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7PWQ6

Entry ID Method Resolution Chain Position Source
AF-Q7PWQ6-F1 Predicted AlphaFoldDB

No variants for Q7PWQ6

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7PWQ6

1 associated diseases with Q7PWQ6

[MIM: 125630]: Vibratory urticaria (VBU)

An autosomal dominant disorder characterized by localized hives and systemic manifestations in response to dermal vibration, with coincident degranulation of mast cells and increased histamine levels in serum. {ECO:0000269|PubMed:26841242}. Note=The disease is caused by variants affecting the gene represented in this entry.

Without disease ID
  • An autosomal dominant disorder characterized by localized hives and systemic manifestations in response to dermal vibration, with coincident degranulation of mast cells and increased histamine levels in serum. {ECO:0000269|PubMed:26841242}. Note=The disease is caused by variants affecting the gene represented in this entry.

No regional properties for Q7PWQ6

Type Name Position InterPro Accession
No domain, repeats, and functional sites for Q7PWQ6

Functions

Description
EC Number
Subcellular Localization
  • Cytoplasm
  • Mitochondrion intermembrane space
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

2 GO annotations of cellular component

Name Definition
cytoplasm The contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
mitochondrial intermembrane space The region between the inner and outer lipid bilayers of the mitochondrial envelope.

4 GO annotations of molecular function

Name Definition
2 iron, 2 sulfur cluster binding Binding to a 2 iron, 2 sulfur (2Fe-2S) cluster; this cluster consists of two iron atoms, with two inorganic sulfur atoms found between the irons and acting as bridging ligands.
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
electron transfer activity Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MNFVQENNHV LYLWAGTVGP EIEQEVNAIK TIPNVQVNVE NVERLQLAEY GKSQFDVILA
70 80 90 100 110 120
QVATGNSTLV TLLVKLLKPK GKCVFRDDSA ASIEQARSNL LLAGFINIVA SDSNVYVAEK
130 140 150 160 170 180
PDYEVGSKSK LSFAKKSNVA AVWKLDDNEE EERIDDEELL DEDDKAKPTE ESLRVCGTTG
190 200 210 220 230 240
KRKACKDCSC GLAEELDAEA KGKALTDTSA AKSSCGSCYL GDAFRCATCP YLGMPAFKPG
250
EKIVLTDTQM QADI