Q7PWB8

PR
Gene name
AGAP009023
Protein name
Probable cytosolic Fe-S cluster assembly factor AGAP009023
Names
Species
Anopheles gambiae (African malaria mosquito)
KEGG Pathway
aga:AgaP_AGAP009023
EC number
Protein Class

Descriptions

The autoinhibited protein was predicted that may have potential autoinhibitory elements via cis-regPred.

Autoinhibitory domains (AIDs)

5-82 (Predicted disordered autoinhibitory region) PR

Target domain

Relief mechanism

Assay

cis-regPred

Accessory elements

No accessory elements

References

Autoinhibited structure

Activated structure

1 structures for Q7PWB8

Entry ID Method Resolution Chain Position Source
AF-Q7PWB8-F1 Predicted AlphaFoldDB

No variants for Q7PWB8

Variant ID(s) Position Change Description Diseaes Association Provenance
No variants for Q7PWB8

No associated diseases with Q7PWB8

2 regional properties for Q7PWB8

Type Name Position InterPro Accession
domain Iron hydrogenase, small subunit 412 - 468 IPR003149
domain Iron hydrogenase, large subunit, C-terminal 112 - 404 IPR004108

Functions

Description
EC Number
Subcellular Localization
PANTHER Family
PANTHER Subfamily
PANTHER Protein Class
PANTHER Pathway Category No pathway information available

1 GO annotations of cellular component

Name Definition
CIA complex The cytosolic iron-sulfur protein assembly (CIA) complex mediates the incorporation of iron-sulfur clusters into apoproteins involved in DNA metabolism and genomic integrity.

2 GO annotations of molecular function

Name Definition
4 iron, 4 sulfur cluster binding Binding to a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
metal ion binding Binding to a metal ion.

1 GO annotations of biological process

Name Definition
iron-sulfur cluster assembly The incorporation of iron and exogenous sulfur into a metallo-sulfur cluster.

No homologous proteins in AiPD

UniProt AC Gene Name Protein Name Species Evidence Code
No homologous proteins
10 20 30 40 50 60
MSRFSSALQL TDLDDFITPS QECIKPVKIE TSKSKTGAKI TIQEDGSYVQ ESSSGIQKLE
70 80 90 100 110 120
KVEITLADCL ACSGCITSAE GVLISQQSQE ELLRVMNANN LAKLNNQRDE IKFVVFTVSQ
130 140 150 160 170 180
QPILSLARKY NLTPEDTFEH IAGYFKKLGA DMVVDTKIAD DLALIECRNE FIERYNTNRK
190 200 210 220 230 240
LLPMLASSCP GWVCYAEKTH GNFILPYIAT TRSPQQIMGV LVKQYLAKQL QTTGDRIYHV
250 260 270 280 290 300
TVMPCYDKKL EASREDFFSE VENSRDVDCV ITSIEIEQML NSLDLPSLQL VERCAIDWPW
310 320 330 340 350 360
PTVRPSAFVW GHESSGSGGY AEYIFKYAAR KLFNVQLDTV AFKPLRNNDM REAVLEQNGQ
370 380 390 400 410 420
VLMRFAIANG FRNIQNMVQK LKRGKSTYDY VEIMACPSGC LNGGAQIRPE EGRAARELTA
430 440 450 460 470
ELECMYRSLP QSTPENDCVQ TMYATFFDSE GDLNKRQSLL HTSYHQIEKI NSALNIKW